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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAD2L1
All Species:
32.73
Human Site:
T189
Identified Species:
48
UniProt:
Q13257
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13257
NP_002349.1
205
23510
T189
R
L
R
S
F
T
T
T
I
H
K
V
N
S
M
Chimpanzee
Pan troglodytes
XP_517581
196
22483
I181
L
R
S
F
T
T
T
I
H
K
V
N
S
M
V
Rhesus Macaque
Macaca mulatta
XP_001084989
205
23614
T189
R
L
R
S
F
T
T
T
I
H
K
V
N
S
M
Dog
Lupus familis
XP_533278
205
23552
T189
R
L
R
S
F
T
T
T
I
H
K
V
N
S
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1B5
205
23580
T189
R
L
R
S
F
T
T
T
I
H
K
V
N
S
M
Rat
Rattus norvegicus
NP_001100064
205
23520
T189
R
L
R
S
F
T
T
T
I
H
K
V
N
S
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513397
205
23385
T189
R
L
R
S
F
T
T
T
I
H
K
V
N
S
M
Chicken
Gallus gallus
XP_420629
206
23693
T190
R
L
R
S
F
T
T
T
I
H
K
V
N
S
M
Frog
Xenopus laevis
NP_001080741
203
23361
I188
L
R
S
F
T
T
T
I
H
K
V
N
S
M
V
Zebra Danio
Brachydanio rerio
NP_001017739
202
23158
I187
L
R
S
F
T
T
S
I
H
K
V
N
S
M
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001023563
203
23510
T188
V
Q
L
R
S
F
S
T
S
V
H
S
V
N
T
Sea Urchin
Strong. purpuratus
XP_001178696
206
23671
S190
R
L
R
S
F
T
T
S
I
H
K
V
D
A
M
Poplar Tree
Populus trichocarpa
XP_002311730
207
23536
K189
K
L
H
S
F
D
T
K
I
H
K
V
D
T
L
Maize
Zea mays
Q9XFH3
208
23486
K189
K
L
H
S
F
D
T
K
I
H
K
V
D
T
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU93
209
23713
K190
K
L
H
G
F
D
T
K
I
H
K
V
D
T
L
Baker's Yeast
Sacchar. cerevisiae
P40958
196
22266
F181
E
V
V
Q
F
K
T
F
S
T
N
D
H
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
97.5
97.5
N.A.
94.1
94.1
N.A.
93.6
86.8
80.4
74.1
N.A.
N.A.
N.A.
50.2
65
Protein Similarity:
100
95.6
97.5
98.5
N.A.
96
97
N.A.
97.5
92.2
89.2
86.8
N.A.
N.A.
N.A.
72.1
77.6
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
100
100
13.3
6.6
N.A.
N.A.
N.A.
6.6
80
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
100
100
26.6
26.6
N.A.
N.A.
N.A.
20
100
Percent
Protein Identity:
46.8
43.7
N.A.
44
41.4
N.A.
Protein Similarity:
67.6
65.8
N.A.
65.5
59.5
N.A.
P-Site Identity:
53.3
53.3
N.A.
46.6
13.3
N.A.
P-Site Similarity:
80
80
N.A.
73.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
19
0
0
0
0
0
7
25
0
0
% D
% Glu:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
19
75
7
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
19
0
0
0
0
0
19
69
7
0
7
0
0
% H
% Ile:
0
0
0
0
0
0
0
19
69
0
0
0
0
0
0
% I
% Lys:
19
0
0
0
0
7
0
19
0
19
69
0
0
7
0
% K
% Leu:
19
69
7
0
0
0
0
0
0
0
0
0
0
0
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
50
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
7
19
44
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
50
19
50
7
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
19
63
7
0
13
7
13
0
0
7
19
44
0
% S
% Thr:
0
0
0
0
19
69
88
50
0
7
0
0
0
19
7
% T
% Val:
7
7
7
0
0
0
0
0
0
7
19
69
7
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _