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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAD2L1
All Species:
36.97
Human Site:
S195
Identified Species:
54.22
UniProt:
Q13257
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13257
NP_002349.1
205
23510
S195
T
T
I
H
K
V
N
S
M
V
A
Y
K
I
P
Chimpanzee
Pan troglodytes
XP_517581
196
22483
M187
T
I
H
K
V
N
S
M
V
A
Y
K
I
P
V
Rhesus Macaque
Macaca mulatta
XP_001084989
205
23614
S195
T
T
I
H
K
V
N
S
M
V
A
Y
K
I
P
Dog
Lupus familis
XP_533278
205
23552
S195
T
T
I
H
K
V
N
S
M
V
A
Y
K
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1B5
205
23580
S195
T
T
I
H
K
V
N
S
M
V
A
Y
K
T
P
Rat
Rattus norvegicus
NP_001100064
205
23520
S195
T
T
I
H
K
V
N
S
M
V
A
Y
K
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513397
205
23385
S195
T
T
I
H
K
V
N
S
M
V
A
Y
K
I
P
Chicken
Gallus gallus
XP_420629
206
23693
S196
T
T
I
H
K
V
N
S
M
V
A
Y
K
K
D
Frog
Xenopus laevis
NP_001080741
203
23361
M194
T
I
H
K
V
N
S
M
V
A
Y
K
K
I
D
Zebra Danio
Brachydanio rerio
NP_001017739
202
23158
M193
S
I
H
K
V
N
S
M
V
A
Y
K
R
T
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001023563
203
23510
N194
S
T
S
V
H
S
V
N
T
N
V
Q
Y
K
A
Sea Urchin
Strong. purpuratus
XP_001178696
206
23671
A196
T
S
I
H
K
V
D
A
M
V
S
Y
K
L
M
Poplar Tree
Populus trichocarpa
XP_002311730
207
23536
T195
T
K
I
H
K
V
D
T
L
V
S
Y
K
N
D
Maize
Zea mays
Q9XFH3
208
23486
T195
T
K
I
H
K
V
D
T
L
V
S
Y
K
K
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU93
209
23713
T196
T
K
I
H
K
V
D
T
L
V
S
Y
K
N
D
Baker's Yeast
Sacchar. cerevisiae
P40958
196
22266
K187
T
F
S
T
N
D
H
K
V
G
A
Q
V
S
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
97.5
97.5
N.A.
94.1
94.1
N.A.
93.6
86.8
80.4
74.1
N.A.
N.A.
N.A.
50.2
65
Protein Similarity:
100
95.6
97.5
98.5
N.A.
96
97
N.A.
97.5
92.2
89.2
86.8
N.A.
N.A.
N.A.
72.1
77.6
P-Site Identity:
100
6.6
100
100
N.A.
93.3
93.3
N.A.
100
86.6
20
0
N.A.
N.A.
N.A.
6.6
60
P-Site Similarity:
100
20
100
100
N.A.
93.3
93.3
N.A.
100
86.6
33.3
26.6
N.A.
N.A.
N.A.
20
93.3
Percent
Protein Identity:
46.8
43.7
N.A.
44
41.4
N.A.
Protein Similarity:
67.6
65.8
N.A.
65.5
59.5
N.A.
P-Site Identity:
53.3
53.3
N.A.
53.3
13.3
N.A.
P-Site Similarity:
80
80
N.A.
80
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
0
19
50
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
25
0
0
0
0
0
0
0
32
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% G
% His:
0
0
19
69
7
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
19
69
0
0
0
0
0
0
0
0
0
7
32
0
% I
% Lys:
0
19
0
19
69
0
0
7
0
0
0
19
75
19
0
% K
% Leu:
0
0
0
0
0
0
0
0
19
0
0
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
19
50
0
0
0
0
0
7
% M
% Asn:
0
0
0
0
7
19
44
7
0
7
0
0
0
13
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
38
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% R
% Ser:
13
7
13
0
0
7
19
44
0
0
25
0
0
7
0
% S
% Thr:
88
50
0
7
0
0
0
19
7
0
0
0
0
19
0
% T
% Val:
0
0
0
7
19
69
7
0
25
69
7
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
19
69
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _