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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRM1 All Species: 22.42
Human Site: S349 Identified Species: 49.33
UniProt: Q13255 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13255 NP_000829.2 1194 132367 S349 L Q S P E V R S F D D Y F L K
Chimpanzee Pan troglodytes NP_001158173 1194 132333 S349 L Q S P E V R S F D D Y F L K
Rhesus Macaque Macaca mulatta A3QP01 839 95041 C59 D Y L Q V P M C K E Y E T K V
Dog Lupus familis XP_850365 1190 131926 S349 L Q S P E V R S F D D Y F L K
Cat Felis silvestris
Mouse Mus musculus P97772 1199 133194 S349 L Q S P E V R S F D D Y F L K
Rat Rattus norvegicus P23385 1199 133218 S349 L Q S P E V R S F D D Y F L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511915 1153 127609 W342 L Q S P D V K W F D D Y Y L K
Chicken Gallus gallus XP_419652 1152 127641 S341 L Q S P E V L S F D D Y Y L K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5U9X3 867 97118 A87 M I N A V E M A N K S P M L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91685 976 108467 R196 T R F D L F A R T V P P D T F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09630 999 113258 Q219 L R L F R I A Q V S P A S T N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 21 95.7 N.A. 94.5 94.5 N.A. 62.4 85.3 N.A. 21.6 N.A. 32.6 N.A. 24.9 N.A.
Protein Similarity: 100 99.9 34.2 97.5 N.A. 96.8 96.6 N.A. 75.6 90.1 N.A. 37.5 N.A. 48.7 N.A. 40.8 N.A.
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 73.3 86.6 N.A. 6.6 N.A. 0 N.A. 6.6 N.A.
P-Site Similarity: 100 100 6.6 100 N.A. 100 100 N.A. 93.3 93.3 N.A. 26.6 N.A. 6.6 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 19 10 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 10 10 0 0 0 0 64 64 0 10 0 0 % D
% Glu: 0 0 0 0 55 10 0 0 0 10 0 10 0 0 0 % E
% Phe: 0 0 10 10 0 10 0 0 64 0 0 0 46 0 10 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 10 0 10 10 0 0 0 10 64 % K
% Leu: 73 0 19 0 10 0 10 0 0 0 0 0 0 73 0 % L
% Met: 10 0 0 0 0 0 19 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 10 % N
% Pro: 0 0 0 64 0 10 0 0 0 0 19 19 0 0 0 % P
% Gln: 0 64 0 10 0 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 19 0 0 10 0 46 10 0 0 0 0 0 0 0 % R
% Ser: 0 0 64 0 0 0 0 55 0 10 10 0 10 0 10 % S
% Thr: 10 0 0 0 0 0 0 0 10 0 0 0 10 19 0 % T
% Val: 0 0 0 0 19 64 0 0 10 10 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 10 64 19 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _