KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SFRS6
All Species:
1.82
Human Site:
T146
Identified Species:
3.08
UniProt:
Q13247
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13247
NP_006266.2
344
39587
T146
A
D
A
H
K
E
R
T
N
E
G
V
I
E
F
Chimpanzee
Pan troglodytes
Q5R1W5
221
25469
T25
V
D
N
L
T
Y
R
T
S
P
D
T
L
R
R
Rhesus Macaque
Macaca mulatta
XP_001113510
464
53241
K140
A
D
A
H
K
G
R
K
N
E
G
V
I
E
F
Dog
Lupus familis
XP_534422
287
32895
G91
G
S
R
S
G
G
G
G
Y
S
S
R
R
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE97
489
55961
K140
A
D
A
H
K
G
R
K
N
E
G
V
I
E
F
Rat
Rattus norvegicus
Q09167
269
30873
R73
R
V
T
I
E
H
A
R
A
R
S
R
G
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512981
401
44678
R168
R
R
R
R
S
Y
S
R
S
R
S
H
S
R
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079647
667
76917
A142
A
D
A
H
K
E
R
A
N
E
G
V
I
E
F
Zebra Danio
Brachydanio rerio
Q6NYA0
245
27457
N48
I
R
D
I
D
L
K
N
R
R
G
G
P
P
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26686
376
42795
R156
A
D
A
H
K
Q
R
R
N
E
G
V
V
E
F
Honey Bee
Apis mellifera
XP_391860
342
39488
Q146
D
L
K
D
Y
M
R
Q
A
G
E
V
T
Y
A
Nematode Worm
Caenorhab. elegans
Q23120
281
32403
F85
E
E
R
S
G
S
G
F
R
G
R
E
P
T
F
Sea Urchin
Strong. purpuratus
XP_798746
311
35431
S115
G
G
G
G
G
G
G
S
R
S
S
Q
R
Y
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22315
303
33711
D107
G
G
G
R
G
R
G
D
G
G
S
R
G
P
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.8
56.9
68.9
N.A.
56
54.9
N.A.
58.5
N.A.
43.4
22.6
N.A.
56.1
61
45.9
60.4
Protein Similarity:
100
43
63.7
72.9
N.A.
61.9
62.2
N.A.
67
N.A.
47
32.5
N.A.
66.7
72.3
59
70.3
P-Site Identity:
100
20
86.6
0
N.A.
86.6
0
N.A.
0
N.A.
93.3
13.3
N.A.
80
13.3
6.6
0
P-Site Similarity:
100
33.3
86.6
0
N.A.
86.6
6.6
N.A.
6.6
N.A.
93.3
20
N.A.
93.3
13.3
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
0
36
0
0
0
8
8
15
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
43
8
8
8
0
0
8
0
0
8
0
0
0
0
% D
% Glu:
8
8
0
0
8
15
0
0
0
36
8
8
0
36
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
50
% F
% Gly:
22
15
15
8
29
29
29
8
8
22
43
8
15
8
8
% G
% His:
0
0
0
36
0
8
0
0
0
0
0
8
0
0
0
% H
% Ile:
8
0
0
15
0
0
0
0
0
0
0
0
29
0
0
% I
% Lys:
0
0
8
0
36
0
8
15
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
8
0
8
0
0
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
8
36
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
15
15
0
% P
% Gln:
0
0
0
0
0
8
0
8
0
0
0
8
0
0
0
% Q
% Arg:
15
15
22
15
0
8
50
22
22
22
8
22
15
15
15
% R
% Ser:
0
8
0
15
8
8
8
8
15
15
36
0
8
0
22
% S
% Thr:
0
0
8
0
8
0
0
15
0
0
0
8
8
15
0
% T
% Val:
8
8
0
0
0
0
0
0
0
0
0
43
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
15
0
0
8
0
0
0
0
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _