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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAA1
All Species:
21.82
Human Site:
S541
Identified Species:
40
UniProt:
Q13131
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13131
NP_006242.5
559
64009
S541
D
L
T
P
R
P
G
S
H
T
I
E
F
F
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086285
574
65620
S556
D
L
T
P
R
P
G
S
H
T
I
E
F
F
E
Dog
Lupus familis
XP_536491
563
64691
S545
D
L
T
P
R
P
G
S
H
T
I
E
F
F
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5EG47
559
63911
S541
D
V
A
P
R
P
G
S
H
T
I
E
F
F
E
Rat
Rattus norvegicus
P54645
559
63955
S541
D
V
A
P
R
P
G
S
H
T
I
E
F
F
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506315
519
59478
E508
S
H
T
I
E
F
F
E
M
C
A
N
L
I
K
Chicken
Gallus gallus
Q9IA88
798
88848
E708
L
L
S
E
L
Q
R
E
N
S
F
E
L
A
F
Frog
Xenopus laevis
NP_001083882
560
64031
S542
D
L
L
P
R
P
G
S
H
T
I
E
F
F
E
Zebra Danio
Brachydanio rerio
NP_001103756
573
65002
A535
K
V
A
E
G
S
L
A
S
S
L
T
S
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623371
515
58559
C506
T
M
E
F
F
E
M
C
A
A
L
I
T
Q
L
Nematode Worm
Caenorhab. elegans
Q95ZQ4
626
70425
P600
S
C
D
V
T
P
P
P
S
P
G
G
A
K
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
L524
P
Q
F
L
F
L
D
L
C
A
A
F
L
A
Q
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
L622
F
L
H
L
T
T
K
L
I
M
E
L
A
V
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.2
92.5
N.A.
98.7
99.1
N.A.
89.2
27
88.7
84.4
N.A.
N.A.
62.2
53.5
N.A.
Protein Similarity:
100
N.A.
97.3
93.7
N.A.
99.4
99.6
N.A.
91
43.1
94.6
90.9
N.A.
N.A.
75.1
66.4
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
86.6
86.6
N.A.
6.6
13.3
93.3
0
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
13.3
33.3
93.3
26.6
N.A.
N.A.
13.3
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
45
33.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.4
51.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
24
0
0
0
0
8
8
16
16
0
16
16
0
% A
% Cys:
0
8
0
0
0
0
0
8
8
8
0
0
0
0
0
% C
% Asp:
47
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
16
8
8
0
16
0
0
8
54
0
0
47
% E
% Phe:
8
0
8
8
16
8
8
0
0
0
8
8
47
47
8
% F
% Gly:
0
0
0
0
8
0
47
0
0
0
8
8
0
0
0
% G
% His:
0
8
8
0
0
0
0
0
47
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
8
0
47
8
0
8
0
% I
% Lys:
8
0
0
0
0
0
8
0
0
0
0
0
0
8
8
% K
% Leu:
8
47
8
16
8
8
8
16
0
0
16
8
24
0
16
% L
% Met:
0
8
0
0
0
0
8
0
8
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
8
% N
% Pro:
8
0
0
47
0
54
8
8
0
8
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
8
0
0
0
0
0
0
0
8
8
% Q
% Arg:
0
0
0
0
47
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
16
0
8
0
0
8
0
47
16
16
0
0
8
8
0
% S
% Thr:
8
0
31
0
16
8
0
0
0
47
0
8
8
0
0
% T
% Val:
0
24
0
8
0
0
0
0
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _