KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPP2
All Species:
3.03
Human Site:
S146
Identified Species:
11.11
UniProt:
Q13103
Number Species:
6
Phosphosite Substitution
Charge Score:
0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13103
NP_008875.1
211
24338
S146
S
T
S
E
S
Y
S
S
E
E
M
I
F
G
D
Chimpanzee
Pan troglodytes
XP_001151806
212
24541
S146
S
T
S
E
S
Y
S
S
S
E
E
M
I
F
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852985
358
39372
E216
S
S
E
S
N
S
S
E
E
L
H
S
E
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1I3
203
23118
E139
S
S
E
S
N
S
S
E
E
M
M
F
G
D
M
Rat
Rattus norvegicus
Q62740
203
23152
E139
T
S
E
S
N
S
S
E
E
M
I
F
G
D
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510561
231
26105
V162
A
A
S
R
S
N
D
V
F
I
F
L
G
G
Q
Chicken
Gallus gallus
Q710A0
192
21630
V128
E
V
S
S
E
Q
I
V
N
V
I
V
R
C
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
N.A.
36
N.A.
66.3
64.9
N.A.
38
38.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.6
N.A.
44.6
N.A.
77.7
76.7
N.A.
54.9
56.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
60
N.A.
20
N.A.
26.6
13.3
N.A.
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
66.6
N.A.
33.3
N.A.
40
40
N.A.
33.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
15
0
0
0
0
0
0
0
0
0
0
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% C
% Asp:
0
0
0
0
0
0
15
0
0
0
0
0
0
29
15
% D
% Glu:
15
0
43
29
15
0
0
43
58
29
15
0
15
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
15
0
15
29
15
15
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
43
29
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
15
% H
% Ile:
0
0
0
0
0
0
15
0
0
15
29
15
15
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
15
0
15
0
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
29
29
15
0
0
29
% M
% Asn:
0
0
0
0
43
15
0
0
15
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
15
% Q
% Arg:
0
0
0
15
0
0
0
0
0
0
0
0
15
0
0
% R
% Ser:
58
43
58
58
43
43
72
29
15
0
0
15
0
0
0
% S
% Thr:
15
29
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
15
0
0
0
0
0
29
0
15
0
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
29
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _