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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSTF3
All Species:
39.7
Human Site:
Y343
Identified Species:
67.18
UniProt:
Q12996
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12996
NP_001317.1
717
82922
Y343
L
K
K
N
M
L
L
Y
F
A
Y
A
D
Y
E
Chimpanzee
Pan troglodytes
XP_001143931
749
86255
Y375
L
K
K
N
M
L
L
Y
F
A
Y
A
D
Y
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533159
717
82899
Y343
L
K
K
N
M
L
L
Y
F
A
Y
A
D
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99LI7
717
82858
Y343
L
K
K
N
M
L
L
Y
F
A
Y
A
D
Y
E
Rat
Rattus norvegicus
NP_001071140
590
69247
I272
R
T
E
D
Q
T
L
I
T
K
R
V
M
F
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507079
820
94279
Y446
L
K
K
N
M
L
L
Y
F
A
Y
A
D
Y
E
Chicken
Gallus gallus
NP_001012586
718
83053
Y344
L
K
K
N
M
L
L
Y
F
A
Y
A
D
Y
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998218
716
82797
Y343
L
K
K
N
M
L
L
Y
F
S
F
A
D
Y
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25991
765
88196
Y376
L
N
R
N
A
L
L
Y
F
A
Y
A
D
F
E
Honey Bee
Apis mellifera
XP_393870
713
82097
Y340
L
S
K
N
M
L
L
Y
F
A
H
A
D
F
E
Nematode Worm
Caenorhab. elegans
NP_495825
735
84603
Y331
M
K
E
S
K
L
L
Y
F
A
Y
A
D
F
Q
Sea Urchin
Strong. purpuratus
XP_796577
557
65419
P239
K
G
L
N
R
N
N
P
S
V
P
P
T
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25298
677
79942
A344
I
L
Y
T
A
L
L
A
N
P
D
S
P
S
L
Red Bread Mold
Neurospora crassa
Q7S1Y0
1167
128472
D665
E
D
G
D
G
A
A
D
N
I
K
K
A
P
I
Conservation
Percent
Protein Identity:
100
95.7
N.A.
99.8
N.A.
99.3
78.5
N.A.
85.9
98
N.A.
90.7
N.A.
53.5
62.6
48.7
56.9
Protein Similarity:
100
95.7
N.A.
99.8
N.A.
99.5
79.9
N.A.
86.7
99.3
N.A.
95.4
N.A.
71.6
78.2
68.4
67.2
P-Site Identity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
100
100
N.A.
86.6
N.A.
73.3
80
60
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
26.6
N.A.
100
100
N.A.
100
N.A.
86.6
93.3
93.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
21.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.7
35.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
15
8
8
8
0
65
0
72
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
15
0
0
0
8
0
0
8
0
72
0
0
% D
% Glu:
8
0
15
0
0
0
0
0
0
0
0
0
0
0
65
% E
% Phe:
0
0
0
0
0
0
0
0
72
0
8
0
0
29
0
% F
% Gly:
0
8
8
0
8
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
8
0
8
0
0
0
0
8
% I
% Lys:
8
58
58
0
8
0
0
0
0
8
8
8
0
0
0
% K
% Leu:
65
8
8
0
0
79
86
0
0
0
0
0
0
0
8
% L
% Met:
8
0
0
0
58
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
8
0
72
0
8
8
0
15
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
8
8
8
8
8
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
8
0
8
0
8
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
8
0
8
0
0
0
0
8
8
0
8
0
8
0
% S
% Thr:
0
8
0
8
0
8
0
0
8
0
0
0
8
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
72
0
0
58
0
0
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _