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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSTF3
All Species:
31.52
Human Site:
Y328
Identified Species:
53.33
UniProt:
Q12996
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12996
NP_001317.1
717
82922
Y328
S
D
E
A
A
N
I
Y
E
R
A
I
S
T
L
Chimpanzee
Pan troglodytes
XP_001143931
749
86255
Y360
S
D
E
A
A
N
I
Y
E
R
A
I
S
T
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533159
717
82899
Y328
S
D
E
A
A
N
I
Y
E
R
A
I
S
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99LI7
717
82858
Y328
S
D
E
A
A
N
I
Y
E
R
A
I
S
T
L
Rat
Rattus norvegicus
NP_001071140
590
69247
Q257
D
M
W
K
K
Y
I
Q
W
E
K
S
N
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507079
820
94279
Y431
S
D
E
A
A
N
I
Y
E
R
A
I
S
T
L
Chicken
Gallus gallus
NP_001012586
718
83053
Y329
S
D
E
A
A
N
I
Y
E
R
A
I
S
T
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998218
716
82797
Y328
S
D
E
A
A
N
I
Y
E
R
A
I
G
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25991
765
88196
L361
A
D
E
C
A
N
I
L
E
R
S
I
N
G
V
Honey Bee
Apis mellifera
XP_393870
713
82097
F325
S
D
E
A
A
T
M
F
E
R
A
T
S
T
L
Nematode Worm
Caenorhab. elegans
NP_495825
735
84603
Y316
K
L
E
T
I
S
L
Y
E
R
A
I
T
G
L
Sea Urchin
Strong. purpuratus
XP_796577
557
65419
A224
Y
M
N
A
R
R
V
A
K
E
Y
E
A
I
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25298
677
79942
S329
Y
D
Y
S
M
Y
I
S
E
N
S
D
R
Q
N
Red Bread Mold
Neurospora crassa
Q7S1Y0
1167
128472
E650
Q
E
M
T
A
A
Q
E
S
K
A
G
S
D
N
Conservation
Percent
Protein Identity:
100
95.7
N.A.
99.8
N.A.
99.3
78.5
N.A.
85.9
98
N.A.
90.7
N.A.
53.5
62.6
48.7
56.9
Protein Similarity:
100
95.7
N.A.
99.8
N.A.
99.5
79.9
N.A.
86.7
99.3
N.A.
95.4
N.A.
71.6
78.2
68.4
67.2
P-Site Identity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
100
100
N.A.
93.3
N.A.
53.3
73.3
46.6
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
20
N.A.
100
100
N.A.
93.3
N.A.
80
86.6
66.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
21.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.7
35.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
65
72
8
0
8
0
0
72
0
8
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
72
0
0
0
0
0
0
0
0
0
8
0
8
0
% D
% Glu:
0
8
72
0
0
0
0
8
79
15
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
8
15
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
72
0
0
0
0
65
0
8
0
% I
% Lys:
8
0
0
8
8
0
0
0
8
8
8
0
0
0
0
% K
% Leu:
0
8
0
0
0
0
8
8
0
0
0
0
0
0
72
% L
% Met:
0
15
8
0
8
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
58
0
0
0
8
0
0
15
0
15
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
8
0
0
0
0
0
8
8
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
8
8
0
0
0
72
0
0
8
0
0
% R
% Ser:
58
0
0
8
0
8
0
8
8
0
15
8
58
0
0
% S
% Thr:
0
0
0
15
0
8
0
0
0
0
0
8
8
58
8
% T
% Val:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
15
0
8
0
0
15
0
58
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _