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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARE
All Species:
18.48
Human Site:
T431
Identified Species:
31.28
UniProt:
Q12980
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12980
NP_001070818.1
569
63605
T431
R
E
D
D
V
P
F
T
A
R
V
G
G
R
S
Chimpanzee
Pan troglodytes
XP_510703
569
63558
T431
R
D
D
D
V
P
F
T
A
R
V
G
G
R
S
Rhesus Macaque
Macaca mulatta
XP_001118432
569
63094
T431
R
E
D
D
V
P
F
T
A
R
V
G
G
R
S
Dog
Lupus familis
XP_854363
368
40934
P241
G
G
R
S
L
S
T
P
N
A
L
S
F
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VIJ8
569
63599
T431
R
E
D
D
V
P
F
T
A
R
V
G
G
R
S
Rat
Rattus norvegicus
NP_001030108
469
52283
V342
V
L
S
P
N
A
S
V
C
L
Y
S
P
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517960
146
16314
Q19
T
K
A
D
V
C
G
Q
K
F
E
L
K
I
D
Chicken
Gallus gallus
XP_414946
569
63971
T431
Q
D
E
D
M
P
F
T
A
R
V
G
G
R
S
Frog
Xenopus laevis
NP_001083270
580
64646
A442
K
D
E
D
T
P
F
A
A
R
V
G
G
R
S
Zebra Danio
Brachydanio rerio
NP_001020705
596
67120
V458
R
D
E
E
L
P
I
V
T
R
V
T
G
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUB4
610
68769
G471
V
P
A
V
L
V
G
G
H
R
R
E
A
S
E
Honey Bee
Apis mellifera
XP_395986
511
58454
V384
S
Q
Q
Q
T
Q
L
V
K
T
I
I
W
L
L
Nematode Worm
Caenorhab. elegans
Q20069
511
57899
V384
Q
G
V
R
A
K
L
V
V
A
L
L
R
H
Q
Sea Urchin
Strong. purpuratus
XP_792244
494
55249
S367
F
R
M
K
F
G
E
S
L
I
K
V
L
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
91.9
63
N.A.
96.3
77.5
N.A.
23.2
87.5
81.5
75.3
N.A.
37.3
41.4
21.4
39.8
Protein Similarity:
100
100
94.1
63.7
N.A.
98.2
79.4
N.A.
24.7
94.7
89.4
83.5
N.A.
56.3
61.3
42
57.8
P-Site Identity:
100
93.3
100
6.6
N.A.
100
0
N.A.
13.3
73.3
66.6
46.6
N.A.
6.6
0
0
0
P-Site Similarity:
100
100
100
20
N.A.
100
6.6
N.A.
20
100
86.6
73.3
N.A.
13.3
13.3
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
8
8
0
8
43
15
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
29
29
50
0
0
0
0
0
0
0
0
0
0
15
% D
% Glu:
0
22
22
8
0
0
8
0
0
0
8
8
0
0
8
% E
% Phe:
8
0
0
0
8
0
43
0
0
8
0
0
8
0
0
% F
% Gly:
8
15
0
0
0
8
15
8
0
0
0
43
50
8
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
8
8
8
0
8
0
% I
% Lys:
8
8
0
8
0
8
0
0
15
0
8
0
8
0
0
% K
% Leu:
0
8
0
0
22
0
15
0
8
8
15
15
8
15
8
% L
% Met:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
8
0
8
0
50
0
8
0
0
0
0
8
0
0
% P
% Gln:
15
8
8
8
0
8
0
8
0
0
0
0
0
0
8
% Q
% Arg:
36
8
8
8
0
0
0
0
0
58
8
0
8
50
0
% R
% Ser:
8
0
8
8
0
8
8
8
0
0
0
15
0
15
58
% S
% Thr:
8
0
0
0
15
0
8
36
8
8
0
8
0
0
0
% T
% Val:
15
0
8
8
36
8
0
29
8
0
50
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _