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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARE
All Species:
9.09
Human Site:
S500
Identified Species:
15.38
UniProt:
Q12980
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12980
NP_001070818.1
569
63605
S500
H
E
R
A
A
I
L
S
V
P
A
A
Q
N
P
Chimpanzee
Pan troglodytes
XP_510703
569
63558
S500
H
E
R
A
A
I
L
S
V
P
A
A
Q
N
P
Rhesus Macaque
Macaca mulatta
XP_001118432
569
63094
S500
H
E
R
A
A
I
L
S
V
P
A
A
Q
N
P
Dog
Lupus familis
XP_854363
368
40934
R310
A
Q
N
P
E
D
L
R
M
F
A
R
L
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8VIJ8
569
63599
N500
H
E
R
A
A
I
L
N
V
P
A
A
Q
N
P
Rat
Rattus norvegicus
NP_001030108
469
52283
C411
I
Q
L
H
T
Y
V
C
L
M
A
S
P
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517960
146
16314
I88
N
L
S
R
R
I
A
I
V
L
Q
H
E
E
R
Chicken
Gallus gallus
XP_414946
569
63971
N500
H
E
R
E
A
I
L
N
V
P
A
A
Q
N
P
Frog
Xenopus laevis
NP_001083270
580
64646
N511
I
E
R
E
A
I
L
N
I
P
A
A
Q
N
Q
Zebra Danio
Brachydanio rerio
NP_001020705
596
67120
R527
H
E
R
Q
A
I
L
R
V
P
A
A
Q
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUB4
610
68769
R540
A
D
R
A
A
I
R
R
I
P
A
S
A
N
V
Honey Bee
Apis mellifera
XP_395986
511
58454
D453
S
D
D
R
K
L
L
D
K
L
C
R
L
D
Y
Nematode Worm
Caenorhab. elegans
Q20069
511
57899
A453
M
L
E
T
T
S
Y
A
S
V
K
R
T
L
S
Sea Urchin
Strong. purpuratus
XP_792244
494
55249
E436
K
S
S
S
D
D
L
E
R
E
V
S
T
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
91.9
63
N.A.
96.3
77.5
N.A.
23.2
87.5
81.5
75.3
N.A.
37.3
41.4
21.4
39.8
Protein Similarity:
100
100
94.1
63.7
N.A.
98.2
79.4
N.A.
24.7
94.7
89.4
83.5
N.A.
56.3
61.3
42
57.8
P-Site Identity:
100
100
100
13.3
N.A.
93.3
6.6
N.A.
13.3
86.6
66.6
86.6
N.A.
46.6
6.6
0
13.3
P-Site Similarity:
100
100
100
26.6
N.A.
100
40
N.A.
26.6
93.3
80
86.6
N.A.
66.6
26.6
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
36
58
0
8
8
0
0
72
50
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% C
% Asp:
0
15
8
0
8
15
0
8
0
0
0
0
0
8
0
% D
% Glu:
0
50
8
15
8
0
0
8
0
8
0
0
8
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
43
0
0
8
0
0
0
0
0
0
0
8
0
0
8
% H
% Ile:
15
0
0
0
0
65
0
8
15
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
8
0
0
0
8
0
8
0
0
0
0
% K
% Leu:
0
15
8
0
0
8
72
0
8
15
0
0
15
15
0
% L
% Met:
8
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
8
0
8
0
0
0
0
22
0
0
0
0
0
58
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
58
0
0
8
8
50
% P
% Gln:
0
15
0
8
0
0
0
0
0
0
8
0
50
0
8
% Q
% Arg:
0
0
58
15
8
0
8
22
8
0
0
22
0
0
8
% R
% Ser:
8
8
15
8
0
8
0
22
8
0
0
22
0
8
8
% S
% Thr:
0
0
0
8
15
0
0
0
0
0
0
0
15
0
0
% T
% Val:
0
0
0
0
0
0
8
0
50
8
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _