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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MARE All Species: 5.76
Human Site: S49 Identified Species: 9.74
UniProt: Q12980 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12980 NP_001070818.1 569 63605 S49 P R S R Y A A S N T G D H A D
Chimpanzee Pan troglodytes XP_510703 569 63558 S49 P R S R Y A A S N T G D H A D
Rhesus Macaque Macaca mulatta XP_001118432 569 63094 N49 P R S R Y A V N N T G D H A D
Dog Lupus familis XP_854363 368 40934
Cat Felis silvestris
Mouse Mus musculus Q8VIJ8 569 63599 N49 P R S R Y A V N N T G E H A D
Rat Rattus norvegicus NP_001030108 469 52283
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517960 146 16314
Chicken Gallus gallus XP_414946 569 63971 N49 P R S R Y A V N S S G D T S E
Frog Xenopus laevis NP_001083270 580 64646 P49 P R S C Y A L P N T G D N C D
Zebra Danio Brachydanio rerio NP_001020705 596 67120 N75 Q R S P Y V L N T S G D S T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUB4 610 68769 P49 R K S R K R N P Y A V A N T D
Honey Bee Apis mellifera XP_395986 511 58454 R32 P H V A K H T R D F N Q C T K
Nematode Worm Caenorhab. elegans Q20069 511 57899 I32 S G E K I V S I Y P H R K P A
Sea Urchin Strong. purpuratus XP_792244 494 55249 S15 L S I I L V S S G S K G Y R L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 91.9 63 N.A. 96.3 77.5 N.A. 23.2 87.5 81.5 75.3 N.A. 37.3 41.4 21.4 39.8
Protein Similarity: 100 100 94.1 63.7 N.A. 98.2 79.4 N.A. 24.7 94.7 89.4 83.5 N.A. 56.3 61.3 42 57.8
P-Site Identity: 100 100 86.6 0 N.A. 80 0 N.A. 0 53.3 66.6 33.3 N.A. 20 6.6 0 6.6
P-Site Similarity: 100 100 93.3 0 N.A. 93.3 0 N.A. 0 86.6 73.3 53.3 N.A. 33.3 13.3 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 43 15 0 0 8 0 8 0 29 8 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 8 8 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 0 0 43 0 0 43 % D
% Glu: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 15 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 0 8 0 0 0 0 0 0 8 0 50 8 0 0 0 % G
% His: 0 8 0 0 0 8 0 0 0 0 8 0 29 0 0 % H
% Ile: 0 0 8 8 8 0 0 8 0 0 0 0 0 0 0 % I
% Lys: 0 8 0 8 15 0 0 0 0 0 8 0 8 0 8 % K
% Leu: 8 0 0 0 8 0 15 0 0 0 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 29 36 0 8 0 15 0 0 % N
% Pro: 50 0 0 8 0 0 0 15 0 8 0 0 0 8 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Q
% Arg: 8 50 0 43 0 8 0 8 0 0 0 8 0 8 0 % R
% Ser: 8 8 58 0 0 0 15 22 8 22 0 0 8 8 0 % S
% Thr: 0 0 0 0 0 0 8 0 8 36 0 0 8 22 0 % T
% Val: 0 0 8 0 0 22 22 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 50 0 0 0 15 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _