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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARE
All Species:
31.21
Human Site:
S446
Identified Species:
52.82
UniProt:
Q12980
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12980
NP_001070818.1
569
63605
S446
L
S
T
P
N
A
L
S
F
G
S
P
T
S
S
Chimpanzee
Pan troglodytes
XP_510703
569
63558
S446
L
S
T
P
N
A
L
S
F
G
S
P
T
S
S
Rhesus Macaque
Macaca mulatta
XP_001118432
569
63094
S446
L
S
T
P
N
A
L
S
F
G
S
P
T
S
S
Dog
Lupus familis
XP_854363
368
40934
T256
P
T
S
S
D
D
M
T
L
T
S
P
S
M
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8VIJ8
569
63599
S446
L
S
T
P
N
A
L
S
F
G
S
P
T
S
S
Rat
Rattus norvegicus
NP_001030108
469
52283
P357
E
Q
F
S
R
Q
F
P
S
H
D
L
P
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517960
146
16314
P34
N
V
R
F
V
G
H
P
T
L
L
Q
H
G
L
Chicken
Gallus gallus
XP_414946
569
63971
S446
L
S
T
P
N
A
L
S
F
G
S
P
T
S
S
Frog
Xenopus laevis
NP_001083270
580
64646
S457
L
S
T
P
N
A
L
S
F
G
S
P
T
S
S
Zebra Danio
Brachydanio rerio
NP_001020705
596
67120
S473
L
S
T
P
S
A
L
S
F
G
S
P
T
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUB4
610
68769
D486
D
H
S
S
L
A
S
D
N
I
A
V
Q
P
S
Honey Bee
Apis mellifera
XP_395986
511
58454
L399
K
N
H
L
L
L
Q
L
H
T
Y
V
Q
Y
M
Nematode Worm
Caenorhab. elegans
Q20069
511
57899
F399
M
L
M
Q
L
H
Q
F
Y
Y
I
L
K
P
Y
Sea Urchin
Strong. purpuratus
XP_792244
494
55249
S382
F
S
L
P
L
P
L
S
D
H
R
N
R
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
91.9
63
N.A.
96.3
77.5
N.A.
23.2
87.5
81.5
75.3
N.A.
37.3
41.4
21.4
39.8
Protein Similarity:
100
100
94.1
63.7
N.A.
98.2
79.4
N.A.
24.7
94.7
89.4
83.5
N.A.
56.3
61.3
42
57.8
P-Site Identity:
100
100
100
13.3
N.A.
100
6.6
N.A.
0
100
100
93.3
N.A.
13.3
0
0
26.6
P-Site Similarity:
100
100
100
53.3
N.A.
100
6.6
N.A.
0
100
100
100
N.A.
26.6
6.6
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
58
0
0
0
0
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
8
0
8
8
0
8
0
0
0
8
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
8
8
0
0
8
8
50
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
50
0
0
0
8
0
% G
% His:
0
8
8
0
0
8
8
0
8
15
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
50
8
8
8
29
8
58
8
8
8
8
15
0
8
8
% L
% Met:
8
0
8
0
0
0
8
0
0
0
0
0
0
8
8
% M
% Asn:
8
8
0
0
43
0
0
0
8
0
0
8
0
0
0
% N
% Pro:
8
0
0
58
0
8
0
15
0
0
0
58
8
15
0
% P
% Gln:
0
8
0
8
0
8
15
0
0
0
0
8
15
0
0
% Q
% Arg:
0
0
8
0
8
0
0
0
0
0
8
0
8
0
0
% R
% Ser:
0
58
15
22
8
0
8
58
8
0
58
0
8
58
58
% S
% Thr:
0
8
50
0
0
0
0
8
8
15
0
0
50
0
0
% T
% Val:
0
8
0
0
8
0
0
0
0
0
0
15
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
8
8
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _