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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MARE All Species: 26.97
Human Site: S210 Identified Species: 45.64
UniProt: Q12980 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12980 NP_001070818.1 569 63605 S210 D L K E A Y D S L C T S G V V
Chimpanzee Pan troglodytes XP_510703 569 63558 S210 D L K E A Y D S L C T S G V V
Rhesus Macaque Macaca mulatta XP_001118432 569 63094 S210 D L K E A Y D S L C T S G V V
Dog Lupus familis XP_854363 368 40934 A38 P H K I H Y A A S S L I P P E
Cat Felis silvestris
Mouse Mus musculus Q8VIJ8 569 63599 S210 D L K E A Y D S L C T S G V V
Rat Rattus norvegicus NP_001030108 469 52283 I139 A N A D P S V I N C L H T L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517960 146 16314
Chicken Gallus gallus XP_414946 569 63971 S210 D L K E T Y D S L C T T G V V
Frog Xenopus laevis NP_001083270 580 64646 S221 D L K E A Y D S L C T T G V V
Zebra Danio Brachydanio rerio NP_001020705 596 67120 S237 D L K E A Y D S L C T T G V V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUB4 610 68769 C213 R S I F H D L C T T G L L S T
Honey Bee Apis mellifera XP_395986 511 58454 E181 V A T S D C D E S P Y E L I L
Nematode Worm Caenorhab. elegans Q20069 511 57899 N181 A D N A E E P N K D H P L E E
Sea Urchin Strong. purpuratus XP_792244 494 55249 H164 R L A L A L K H E E K R C G Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 91.9 63 N.A. 96.3 77.5 N.A. 23.2 87.5 81.5 75.3 N.A. 37.3 41.4 21.4 39.8
Protein Similarity: 100 100 94.1 63.7 N.A. 98.2 79.4 N.A. 24.7 94.7 89.4 83.5 N.A. 56.3 61.3 42 57.8
P-Site Identity: 100 100 100 13.3 N.A. 100 6.6 N.A. 0 86.6 93.3 93.3 N.A. 0 6.6 0 13.3
P-Site Similarity: 100 100 100 20 N.A. 100 20 N.A. 0 93.3 100 100 N.A. 0 20 6.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 8 15 8 50 0 8 8 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 8 0 8 0 58 0 0 8 0 0 % C
% Asp: 50 8 0 8 8 8 58 0 0 8 0 0 0 0 0 % D
% Glu: 0 0 0 50 8 8 0 8 8 8 0 8 0 8 15 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 8 0 50 8 0 % G
% His: 0 8 0 0 15 0 0 8 0 0 8 8 0 0 0 % H
% Ile: 0 0 8 8 0 0 0 8 0 0 0 8 0 8 0 % I
% Lys: 0 0 58 0 0 0 8 0 8 0 8 0 0 0 0 % K
% Leu: 0 58 0 8 0 8 8 0 50 0 15 8 22 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 8 0 0 0 0 8 8 0 0 0 0 0 0 % N
% Pro: 8 0 0 0 8 0 8 0 0 8 0 8 8 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 15 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % R
% Ser: 0 8 0 8 0 8 0 50 15 8 0 29 0 8 8 % S
% Thr: 0 0 8 0 8 0 0 0 8 8 50 22 8 0 8 % T
% Val: 8 0 0 0 0 0 8 0 0 0 0 0 0 50 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 58 0 0 0 0 8 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _