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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SF3A3
All Species:
26.36
Human Site:
Y414
Identified Species:
44.62
UniProt:
Q12874
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12874
NP_006793.1
501
58849
Y414
N
C
E
I
C
G
N
Y
T
Y
R
G
P
K
A
Chimpanzee
Pan troglodytes
XP_001170203
457
53624
P384
I
Y
N
P
K
N
L
P
L
G
W
D
G
K
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849980
501
58873
Y414
N
C
E
I
C
G
N
Y
T
Y
R
G
P
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D554
501
58823
Y414
N
C
E
I
C
G
N
Y
T
Y
R
G
P
K
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512163
478
55587
Y391
N
C
E
I
C
G
N
Y
T
Y
R
G
P
K
A
Chicken
Gallus gallus
XP_001232935
501
58871
Y414
N
C
E
I
C
G
N
Y
T
Y
R
G
P
K
A
Frog
Xenopus laevis
NP_001088491
501
58735
F414
N
C
E
I
C
G
N
F
T
Y
R
G
P
K
A
Zebra Danio
Brachydanio rerio
NP_001004289
501
58645
Y414
N
C
E
I
C
G
N
Y
T
Y
R
G
P
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46106
503
58403
F416
N
C
E
I
C
G
N
F
T
Y
K
G
P
K
A
Honey Bee
Apis mellifera
XP_397399
501
58338
F414
N
C
E
I
C
G
N
F
T
Y
K
G
P
K
A
Nematode Worm
Caenorhab. elegans
NP_495799
500
57459
Q413
S
C
E
I
C
G
N
Q
T
Y
K
G
P
K
A
Sea Urchin
Strong. purpuratus
XP_782055
503
58549
Q416
S
C
E
I
C
G
N
Q
T
Y
R
G
P
K
A
Poplar Tree
Populus trichocarpa
XP_002317774
509
59816
Y422
K
C
E
I
C
G
N
Y
S
Y
W
G
R
R
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P19736
530
63011
K429
R
C
E
I
C
S
N
K
V
Y
N
G
R
R
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.2
N.A.
99.8
N.A.
99.1
N.A.
N.A.
92.8
97
91.8
91
N.A.
65.4
72.2
52.6
72.7
Protein Similarity:
100
91.2
N.A.
99.8
N.A.
99.5
N.A.
N.A.
93.8
98.8
97
95.6
N.A.
81.3
85
71.2
86.6
P-Site Identity:
100
6.6
N.A.
100
N.A.
100
N.A.
N.A.
100
100
93.3
100
N.A.
86.6
86.6
80
86.6
P-Site Similarity:
100
6.6
N.A.
100
N.A.
100
N.A.
N.A.
100
100
100
100
N.A.
100
100
93.3
93.3
Percent
Protein Identity:
45.1
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
66
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
66.6
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
80
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
86
% A
% Cys:
0
93
0
0
93
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
93
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
22
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
86
0
0
0
8
0
93
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
93
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
8
0
0
8
0
0
22
0
0
86
0
% K
% Leu:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
65
0
8
0
0
8
93
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
8
0
0
0
0
79
0
8
% P
% Gln:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
58
0
15
15
0
% R
% Ser:
15
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
79
0
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
50
0
93
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _