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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SF3A3
All Species:
42.12
Human Site:
Y163
Identified Species:
71.28
UniProt:
Q12874
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12874
NP_006793.1
501
58849
Y163
E
K
L
D
Y
I
T
Y
L
S
I
F
D
Q
L
Chimpanzee
Pan troglodytes
XP_001170203
457
53624
Y149
L
H
D
C
Y
L
K
Y
I
N
L
K
A
S
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849980
501
58873
Y163
E
K
L
D
Y
I
T
Y
L
S
I
F
D
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D554
501
58823
Y163
E
K
L
D
Y
I
T
Y
L
S
I
F
D
Q
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512163
478
55587
R154
L
F
D
I
P
K
E
R
K
N
T
D
Y
K
R
Chicken
Gallus gallus
XP_001232935
501
58871
Y163
E
K
L
D
Y
I
T
Y
L
S
T
F
D
Q
L
Frog
Xenopus laevis
NP_001088491
501
58735
Y163
E
K
L
D
Y
I
T
Y
L
A
T
F
D
Q
L
Zebra Danio
Brachydanio rerio
NP_001004289
501
58645
Y163
E
K
L
E
Y
V
T
Y
L
S
T
F
D
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46106
503
58403
Y162
E
K
L
D
Y
I
T
Y
L
M
S
F
D
H
V
Honey Bee
Apis mellifera
XP_397399
501
58338
Y163
E
K
I
D
Y
I
T
Y
L
S
T
F
D
H
L
Nematode Worm
Caenorhab. elegans
NP_495799
500
57459
Y163
K
R
V
D
Y
M
T
Y
L
L
N
F
E
K
F
Sea Urchin
Strong. purpuratus
XP_782055
503
58549
Y163
E
K
V
D
Y
V
T
Y
L
S
I
A
D
R
L
Poplar Tree
Populus trichocarpa
XP_002317774
509
59816
Y161
K
P
I
E
Y
S
T
Y
L
D
I
F
S
Q
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P19736
530
63011
E168
A
R
D
L
D
L
N
E
I
F
T
R
D
E
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.2
N.A.
99.8
N.A.
99.1
N.A.
N.A.
92.8
97
91.8
91
N.A.
65.4
72.2
52.6
72.7
Protein Similarity:
100
91.2
N.A.
99.8
N.A.
99.5
N.A.
N.A.
93.8
98.8
97
95.6
N.A.
81.3
85
71.2
86.6
P-Site Identity:
100
13.3
N.A.
100
N.A.
100
N.A.
N.A.
0
93.3
86.6
80
N.A.
73.3
80
40
73.3
P-Site Similarity:
100
40
N.A.
100
N.A.
100
N.A.
N.A.
13.3
93.3
93.3
93.3
N.A.
80
86.6
80
93.3
Percent
Protein Identity:
45.1
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
66
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
46.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
8
0
8
8
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
22
65
8
0
0
0
0
8
0
8
72
0
0
% D
% Glu:
65
0
0
15
0
0
8
8
0
0
0
0
8
8
8
% E
% Phe:
0
8
0
0
0
0
0
0
0
8
0
72
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
15
0
% H
% Ile:
0
0
15
8
0
50
0
0
15
0
36
0
0
0
0
% I
% Lys:
15
65
0
0
0
8
8
0
8
0
0
8
0
15
0
% K
% Leu:
15
0
50
8
0
15
0
0
79
8
8
0
0
0
58
% L
% Met:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
15
8
0
0
0
0
% N
% Pro:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
8
% Q
% Arg:
0
15
0
0
0
0
0
8
0
0
0
8
0
8
8
% R
% Ser:
0
0
0
0
0
8
0
0
0
50
8
0
8
8
0
% S
% Thr:
0
0
0
0
0
0
79
0
0
0
43
0
0
0
0
% T
% Val:
0
0
15
0
0
15
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
86
0
0
86
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _