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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SF3A3
All Species:
39.7
Human Site:
Y139
Identified Species:
67.18
UniProt:
Q12874
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12874
NP_006793.1
501
58849
Y139
D
E
E
G
Y
G
R
Y
L
D
L
H
D
C
Y
Chimpanzee
Pan troglodytes
XP_001170203
457
53624
Q125
E
N
P
S
E
E
A
Q
N
L
V
E
F
T
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849980
501
58873
Y139
D
E
E
G
Y
G
R
Y
L
D
L
H
D
C
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9D554
501
58823
Y139
D
E
E
G
Y
G
R
Y
L
D
L
H
D
C
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512163
478
55587
K130
Y
L
K
Y
I
N
L
K
A
S
E
K
L
D
Y
Chicken
Gallus gallus
XP_001232935
501
58871
Y139
D
E
E
G
Y
G
R
Y
L
D
L
H
D
C
Y
Frog
Xenopus laevis
NP_001088491
501
58735
Y139
D
E
E
G
Y
G
R
Y
M
D
L
H
D
C
Y
Zebra Danio
Brachydanio rerio
NP_001004289
501
58645
Y139
D
E
E
G
Y
G
R
Y
L
D
L
H
D
C
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46106
503
58403
Y138
D
E
E
G
G
G
R
Y
L
D
L
N
E
C
Y
Honey Bee
Apis mellifera
XP_397399
501
58338
Y139
D
E
E
G
Y
G
K
Y
L
D
L
H
E
C
Y
Nematode Worm
Caenorhab. elegans
NP_495799
500
57459
F139
D
E
E
A
Y
G
R
F
L
D
L
H
A
Q
Y
Sea Urchin
Strong. purpuratus
XP_782055
503
58549
Y139
D
E
E
G
Y
G
K
Y
M
D
L
H
E
C
Y
Poplar Tree
Populus trichocarpa
XP_002317774
509
59816
Y137
G
E
E
A
F
G
K
Y
L
D
M
H
E
L
Y
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P19736
530
63011
F144
K
K
D
K
Y
A
L
F
S
S
S
S
D
P
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.2
N.A.
99.8
N.A.
99.1
N.A.
N.A.
92.8
97
91.8
91
N.A.
65.4
72.2
52.6
72.7
Protein Similarity:
100
91.2
N.A.
99.8
N.A.
99.5
N.A.
N.A.
93.8
98.8
97
95.6
N.A.
81.3
85
71.2
86.6
P-Site Identity:
100
0
N.A.
100
N.A.
100
N.A.
N.A.
6.6
100
93.3
100
N.A.
80
86.6
73.3
80
P-Site Similarity:
100
13.3
N.A.
100
N.A.
100
N.A.
N.A.
13.3
100
100
100
N.A.
93.3
100
80
100
Percent
Protein Identity:
45.1
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
66
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
53.3
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
80
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
0
8
8
0
8
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
65
0
% C
% Asp:
72
0
8
0
0
0
0
0
0
79
0
0
50
8
8
% D
% Glu:
8
79
79
0
8
8
0
0
0
0
8
8
29
0
0
% E
% Phe:
0
0
0
0
8
0
0
15
0
0
0
0
8
0
0
% F
% Gly:
8
0
0
65
8
79
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
72
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
8
8
8
0
0
22
8
0
0
0
8
0
0
0
% K
% Leu:
0
8
0
0
0
0
15
0
65
8
72
0
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
15
0
8
0
0
0
0
% M
% Asn:
0
8
0
0
0
8
0
0
8
0
0
8
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
58
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
8
0
0
0
0
8
15
8
8
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
72
0
0
72
0
0
0
0
0
0
86
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _