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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SF3A3
All Species:
29.09
Human Site:
S468
Identified Species:
49.23
UniProt:
Q12874
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12874
NP_006793.1
501
58849
S468
K
L
K
L
Q
K
A
S
E
R
W
Q
P
D
T
Chimpanzee
Pan troglodytes
XP_001170203
457
53624
F426
P
K
A
F
Q
R
H
F
A
E
W
R
H
A
H
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849980
501
58873
S468
K
L
K
L
Q
K
A
S
E
R
W
Q
P
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9D554
501
58823
S468
K
L
K
L
Q
K
A
S
E
R
W
Q
P
D
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512163
478
55587
S445
K
L
K
L
Q
K
A
S
E
R
W
Q
P
D
T
Chicken
Gallus gallus
XP_001232935
501
58871
S468
K
L
K
L
Q
K
A
S
E
R
W
Q
P
D
T
Frog
Xenopus laevis
NP_001088491
501
58735
S468
K
L
K
L
Q
K
S
S
E
R
W
Q
P
D
T
Zebra Danio
Brachydanio rerio
NP_001004289
501
58645
L468
K
L
K
S
Q
K
A
L
E
R
W
Q
P
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46106
503
58403
S470
K
L
K
S
Q
K
Q
S
E
R
W
V
A
D
Q
Honey Bee
Apis mellifera
XP_397399
501
58338
A468
K
L
K
A
Q
K
Q
A
E
R
W
Q
P
E
Q
Nematode Worm
Caenorhab. elegans
NP_495799
500
57459
M467
K
L
K
T
E
K
E
M
A
K
W
N
P
D
I
Sea Urchin
Strong. purpuratus
XP_782055
503
58549
S470
K
L
K
N
N
K
A
S
E
R
W
L
P
E
A
Poplar Tree
Populus trichocarpa
XP_002317774
509
59816
V476
G
I
Q
E
R
Q
G
V
N
K
W
R
P
D
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P19736
530
63011
Q497
P
P
K
P
N
P
S
Q
L
K
V
P
T
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.2
N.A.
99.8
N.A.
99.1
N.A.
N.A.
92.8
97
91.8
91
N.A.
65.4
72.2
52.6
72.7
Protein Similarity:
100
91.2
N.A.
99.8
N.A.
99.5
N.A.
N.A.
93.8
98.8
97
95.6
N.A.
81.3
85
71.2
86.6
P-Site Identity:
100
13.3
N.A.
100
N.A.
100
N.A.
N.A.
100
100
93.3
86.6
N.A.
66.6
66.6
46.6
66.6
P-Site Similarity:
100
26.6
N.A.
100
N.A.
100
N.A.
N.A.
100
100
100
86.6
N.A.
66.6
80
60
73.3
Percent
Protein Identity:
45.1
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
66
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
20
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
60
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
50
8
15
0
0
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
72
0
% D
% Glu:
0
0
0
8
8
0
8
0
72
8
0
0
0
22
0
% E
% Phe:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
8
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
79
8
86
0
0
79
0
0
0
22
0
0
0
0
0
% K
% Leu:
0
79
0
43
0
0
0
8
8
0
0
8
0
0
15
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
15
0
0
0
8
0
0
8
0
0
0
% N
% Pro:
15
8
0
8
0
8
0
0
0
0
0
8
79
0
0
% P
% Gln:
0
0
8
0
72
8
15
8
0
0
0
58
0
0
15
% Q
% Arg:
0
0
0
0
8
8
0
0
0
72
0
15
0
0
0
% R
% Ser:
0
0
0
15
0
0
15
58
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
50
% T
% Val:
0
0
0
0
0
0
0
8
0
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
93
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _