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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SF3A3
All Species:
30.61
Human Site:
S365
Identified Species:
51.79
UniProt:
Q12874
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12874
NP_006793.1
501
58849
S365
E
E
E
E
E
Q
I
S
E
S
E
S
E
D
E
Chimpanzee
Pan troglodytes
XP_001170203
457
53624
E336
E
Y
V
E
I
L
G
E
Q
R
H
L
T
H
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849980
501
58873
S365
E
E
E
E
E
Q
I
S
E
S
E
S
E
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D554
501
58823
S365
E
E
E
E
E
Q
I
S
E
S
E
S
E
D
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512163
478
55587
S342
E
E
E
E
E
Q
I
S
E
S
E
S
E
D
E
Chicken
Gallus gallus
XP_001232935
501
58871
S365
E
E
E
E
E
Q
I
S
E
S
E
S
E
D
E
Frog
Xenopus laevis
NP_001088491
501
58735
S365
E
E
E
E
E
Q
I
S
D
S
E
S
D
D
E
Zebra Danio
Brachydanio rerio
NP_001004289
501
58645
S365
E
E
D
E
E
Q
P
S
E
S
E
S
E
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46106
503
58403
S365
D
D
S
D
V
E
A
S
E
S
D
N
E
D
D
Honey Bee
Apis mellifera
XP_397399
501
58338
A365
D
S
D
A
E
A
S
A
S
E
S
E
E
E
D
Nematode Worm
Caenorhab. elegans
NP_495799
500
57459
V364
E
E
E
E
E
E
I
V
I
E
E
E
E
E
I
Sea Urchin
Strong. purpuratus
XP_782055
503
58549
E365
E
R
E
D
E
D
E
E
H
F
S
D
S
D
S
Poplar Tree
Populus trichocarpa
XP_002317774
509
59816
E366
T
Y
D
E
M
E
A
E
R
E
E
E
E
T
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P19736
530
63011
Q359
A
E
M
D
I
L
T
Q
K
Y
E
A
P
A
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.2
N.A.
99.8
N.A.
99.1
N.A.
N.A.
92.8
97
91.8
91
N.A.
65.4
72.2
52.6
72.7
Protein Similarity:
100
91.2
N.A.
99.8
N.A.
99.5
N.A.
N.A.
93.8
98.8
97
95.6
N.A.
81.3
85
71.2
86.6
P-Site Identity:
100
20
N.A.
100
N.A.
100
N.A.
N.A.
100
100
86.6
86.6
N.A.
33.3
13.3
53.3
26.6
P-Site Similarity:
100
26.6
N.A.
100
N.A.
100
N.A.
N.A.
100
100
100
93.3
N.A.
80
46.6
66.6
33.3
Percent
Protein Identity:
45.1
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
66
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
20
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
40
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
8
15
8
0
0
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
8
22
22
0
8
0
0
8
0
8
8
8
65
15
% D
% Glu:
72
65
58
72
72
22
8
22
50
22
72
22
72
15
58
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
8
0
0
8
0
% H
% Ile:
0
0
0
0
15
0
50
0
8
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
15
0
0
0
0
0
8
0
0
0
% L
% Met:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
50
0
8
8
0
0
0
0
0
8
% Q
% Arg:
0
8
0
0
0
0
0
0
8
8
0
0
0
0
0
% R
% Ser:
0
8
8
0
0
0
8
58
8
58
15
50
8
0
8
% S
% Thr:
8
0
0
0
0
0
8
0
0
0
0
0
8
8
0
% T
% Val:
0
0
8
0
8
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
15
0
0
0
0
0
0
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _