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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMPCA
All Species:
27.88
Human Site:
Y245
Identified Species:
47.18
UniProt:
Q10713
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q10713
NP_055975.1
525
58253
Y245
L
H
S
Y
L
R
N
Y
Y
T
P
D
R
M
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537796
526
58551
Y246
L
H
S
Y
L
R
N
Y
Y
T
P
D
R
M
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9DC61
524
58261
Y244
L
H
S
Y
L
K
N
Y
Y
T
P
D
R
M
V
Rat
Rattus norvegicus
P20069
524
58589
Y244
L
H
S
Y
L
K
N
Y
Y
T
P
D
R
M
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521013
513
57132
V240
Y
Y
T
P
D
R
M
V
L
A
G
V
G
I
E
Chicken
Gallus gallus
NP_001006197
519
57529
Y239
L
H
S
Y
L
R
N
Y
Y
T
P
D
R
M
V
Frog
Xenopus laevis
NP_001089466
518
57691
Y238
L
H
N
Y
L
H
N
Y
Y
T
P
D
R
M
V
Zebra Danio
Brachydanio rerio
NP_001007443
517
57513
Y237
L
H
K
Y
L
Q
S
Y
Y
C
P
E
R
M
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610333
556
61032
H272
L
M
N
Y
L
K
Y
H
H
S
P
K
R
M
V
Honey Bee
Apis mellifera
XP_624556
358
40406
E94
V
Q
K
Y
F
V
N
E
K
S
V
W
E
E
E
Nematode Worm
Caenorhab. elegans
P98080
471
51717
K207
N
I
S
A
Q
Q
L
K
E
W
Q
E
D
H
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZU25
503
54383
D238
Y
A
P
E
S
A
L
D
R
L
N
G
E
L
L
Baker's Yeast
Sacchar. cerevisiae
P11914
482
53319
K218
K
A
L
E
L
T
E
K
Y
L
G
D
W
Q
S
Red Bread Mold
Neurospora crassa
P11913
476
52538
Y212
T
R
T
E
L
V
N
Y
I
K
N
N
Y
T
A
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
90.1
N.A.
91.2
86
N.A.
81.7
82
81.3
78.4
N.A.
47.8
32.1
25.5
N.A.
Protein Similarity:
100
N.A.
N.A.
95.2
N.A.
95
90.4
N.A.
90.4
89.9
90.2
88
N.A.
66.3
46.6
44.5
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
93.3
93.3
N.A.
6.6
100
86.6
66.6
N.A.
46.6
13.3
6.6
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
26.6
100
93.3
86.6
N.A.
80
26.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.6
34.4
29.5
Protein Similarity:
N.A.
N.A.
N.A.
48
54.4
49.1
P-Site Identity:
N.A.
N.A.
N.A.
0
20
20
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
8
0
8
0
0
0
8
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
8
0
0
0
50
8
0
0
% D
% Glu:
0
0
0
22
0
0
8
8
8
0
0
15
15
8
15
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
15
8
8
0
0
% G
% His:
0
50
0
0
0
8
0
8
8
0
0
0
0
8
0
% H
% Ile:
0
8
0
0
0
0
0
0
8
0
0
0
0
8
0
% I
% Lys:
8
0
15
0
0
22
0
15
8
8
0
8
0
0
0
% K
% Leu:
58
0
8
0
72
0
15
0
8
15
0
0
0
8
8
% L
% Met:
0
8
0
0
0
0
8
0
0
0
0
0
0
58
0
% M
% Asn:
8
0
15
0
0
0
58
0
0
0
15
8
0
0
0
% N
% Pro:
0
0
8
8
0
0
0
0
0
0
58
0
0
0
0
% P
% Gln:
0
8
0
0
8
15
0
0
0
0
8
0
0
8
0
% Q
% Arg:
0
8
0
0
0
29
0
0
8
0
0
0
58
0
0
% R
% Ser:
0
0
43
0
8
0
8
0
0
15
0
0
0
0
8
% S
% Thr:
8
0
15
0
0
8
0
0
0
43
0
0
0
8
0
% T
% Val:
8
0
0
0
0
15
0
8
0
0
8
8
0
0
58
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
8
8
0
0
% W
% Tyr:
15
8
0
65
0
0
8
58
58
0
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _