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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMPCA
All Species:
17.27
Human Site:
T177
Identified Species:
29.23
UniProt:
Q10713
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q10713
NP_055975.1
525
58253
T177
V
V
L
Q
P
R
L
T
D
E
E
V
E
M
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537796
526
58551
T178
V
V
L
H
P
R
L
T
D
K
E
I
E
M
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9DC61
524
58261
T176
V
V
L
H
P
R
L
T
D
E
E
I
E
M
T
Rat
Rattus norvegicus
P20069
524
58589
T176
V
V
L
H
P
R
L
T
D
E
E
I
E
M
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521013
513
57132
F178
M
T
R
M
A
V
R
F
E
L
E
D
L
N
M
Chicken
Gallus gallus
NP_001006197
519
57529
T178
S
D
E
E
I
E
M
T
R
M
A
I
R
F
E
Frog
Xenopus laevis
NP_001089466
518
57691
M176
L
T
E
E
E
I
E
M
T
R
M
A
I
R
F
Zebra Danio
Brachydanio rerio
NP_001007443
517
57513
A176
L
D
E
E
I
E
M
A
R
M
A
V
R
F
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610333
556
61032
S204
V
T
L
R
P
T
L
S
D
Q
E
V
S
L
A
Honey Bee
Apis mellifera
XP_624556
358
40406
A33
M
D
M
I
H
A
A
A
Y
R
S
N
T
L
G
Nematode Worm
Caenorhab. elegans
P98080
471
51717
L146
D
V
L
R
N
S
K
L
E
A
S
T
I
D
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZU25
503
54383
L177
V
P
E
M
V
E
V
L
I
D
S
V
R
N
P
Baker's Yeast
Sacchar. cerevisiae
P11914
482
53319
L157
P
E
L
V
L
P
E
L
L
H
T
A
A
Y
S
Red Bread Mold
Neurospora crassa
P11913
476
52538
E151
L
Q
N
S
K
L
E
E
S
A
I
E
R
E
R
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
90.1
N.A.
91.2
86
N.A.
81.7
82
81.3
78.4
N.A.
47.8
32.1
25.5
N.A.
Protein Similarity:
100
N.A.
N.A.
95.2
N.A.
95
90.4
N.A.
90.4
89.9
90.2
88
N.A.
66.3
46.6
44.5
N.A.
P-Site Identity:
100
N.A.
N.A.
80
N.A.
86.6
86.6
N.A.
6.6
6.6
0
6.6
N.A.
46.6
0
20
N.A.
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
93.3
93.3
N.A.
20
26.6
13.3
26.6
N.A.
73.3
20
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.6
34.4
29.5
Protein Similarity:
N.A.
N.A.
N.A.
48
54.4
49.1
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
8
15
0
15
15
15
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
22
0
0
0
0
0
0
36
8
0
8
0
8
0
% D
% Glu:
0
8
29
22
8
22
22
8
15
22
43
8
29
8
15
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
15
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
22
8
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
8
15
8
0
0
8
0
8
29
15
0
0
% I
% Lys:
0
0
0
0
8
0
8
0
0
8
0
0
0
0
0
% K
% Leu:
22
0
50
0
8
8
36
22
8
8
0
0
8
15
0
% L
% Met:
15
0
8
15
0
0
15
8
0
15
8
0
0
29
8
% M
% Asn:
0
0
8
0
8
0
0
0
0
0
0
8
0
15
0
% N
% Pro:
8
8
0
0
36
8
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
8
0
8
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
8
15
0
29
8
0
15
15
0
0
29
8
8
% R
% Ser:
8
0
0
8
0
8
0
8
8
0
22
0
8
0
8
% S
% Thr:
0
22
0
0
0
8
0
36
8
0
8
8
8
0
36
% T
% Val:
43
36
0
8
8
8
8
0
0
0
0
29
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _