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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF1
All Species:
12.42
Human Site:
Y862
Identified Species:
22.78
UniProt:
Q10570
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q10570
NP_037423.2
1443
160884
Y862
G
S
R
Q
S
R
P
Y
L
L
V
H
V
D
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532356
1499
165986
Y918
G
S
R
Q
S
R
P
Y
L
L
V
H
V
D
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPU4
1441
160800
Y860
G
S
R
Q
S
R
P
Y
L
L
V
H
V
D
Q
Rat
Rattus norvegicus
NP_001124043
1386
154862
L844
L
P
L
V
K
E
V
L
L
V
A
L
G
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514888
831
91833
A300
I
L
N
I
G
P
C
A
N
A
A
M
G
E
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108153
1449
162918
Y868
G
Y
N
H
S
R
P
Y
L
L
A
H
V
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V726
1455
164663
L878
G
L
N
G
E
R
P
L
L
L
V
R
T
R
V
Honey Bee
Apis mellifera
XP_624382
1415
160872
M844
G
H
H
G
N
R
P
M
L
L
V
R
L
D
S
Nematode Worm
Caenorhab. elegans
Q9N4C2
1454
162698
I869
G
I
N
Q
A
H
P
I
L
M
A
I
V
D
E
Sea Urchin
Strong. purpuratus
XP_789715
1220
135970
T689
E
G
G
T
K
P
E
T
E
T
E
A
E
S
D
Poplar Tree
Populus trichocarpa
XP_002318462
1455
159431
K892
E
G
P
D
G
T
S
K
L
E
D
S
V
S
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGR0
1442
158057
C873
L
A
D
G
T
I
L
C
Y
H
A
Y
L
F
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SEY2
1456
158155
L862
T
T
H
K
S
P
Y
L
I
L
R
H
A
N
D
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
90.8
N.A.
96.5
92.8
N.A.
50.6
N.A.
N.A.
79.6
N.A.
46.7
54.3
31.5
47.6
Protein Similarity:
100
N.A.
N.A.
92.5
N.A.
98
94.3
N.A.
53.3
N.A.
N.A.
89.2
N.A.
65.5
71
52.2
60.7
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
6.6
N.A.
0
N.A.
N.A.
66.6
N.A.
40
46.6
40
0
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
20
N.A.
6.6
N.A.
N.A.
73.3
N.A.
40
60
60
0
Percent
Protein Identity:
33.1
N.A.
N.A.
32.8
N.A.
28
Protein Similarity:
51.6
N.A.
N.A.
51.8
N.A.
48.7
P-Site Identity:
13.3
N.A.
N.A.
0
N.A.
20
P-Site Similarity:
13.3
N.A.
N.A.
26.6
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
0
8
0
8
39
8
8
0
8
% A
% Cys:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
0
0
0
0
8
0
0
39
24
% D
% Glu:
16
0
0
0
8
8
8
0
8
8
8
0
8
16
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
54
16
8
24
16
0
0
0
0
0
0
0
16
0
0
% G
% His:
0
8
16
8
0
8
0
0
0
8
0
39
0
0
0
% H
% Ile:
8
8
0
8
0
8
0
8
8
0
0
8
0
0
0
% I
% Lys:
0
0
0
8
16
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
16
16
8
0
0
0
8
24
70
54
0
8
16
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
8
0
8
0
0
0
% M
% Asn:
0
0
31
0
8
0
0
0
8
0
0
0
0
8
0
% N
% Pro:
0
8
8
0
0
24
54
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
31
0
0
0
0
0
0
0
0
0
0
31
% Q
% Arg:
0
0
24
0
0
47
0
0
0
0
8
16
0
8
8
% R
% Ser:
0
24
0
0
39
0
8
0
0
0
0
8
0
24
8
% S
% Thr:
8
8
0
8
8
8
0
8
0
8
0
0
8
0
0
% T
% Val:
0
0
0
8
0
0
8
0
0
8
39
0
47
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
31
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _