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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF1
All Species:
4.55
Human Site:
Y448
Identified Species:
8.33
UniProt:
Q10570
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q10570
NP_037423.2
1443
160884
Y448
E
V
D
E
I
E
V
Y
G
S
E
A
Q
S
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532356
1499
165986
G506
V
D
E
I
E
V
Y
G
S
E
A
Q
S
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPU4
1441
160800
G448
V
D
E
I
E
V
Y
G
S
E
A
Q
S
G
T
Rat
Rattus norvegicus
NP_001124043
1386
154862
E448
E
I
E
V
Y
G
S
E
A
Q
S
G
T
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514888
831
91833
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108153
1449
162918
Y448
E
L
D
E
I
E
V
Y
G
S
E
A
Q
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V726
1455
164663
R459
P
T
Q
A
K
S
R
R
I
E
D
E
E
L
E
Honey Bee
Apis mellifera
XP_624382
1415
160872
E450
L
D
I
K
D
P
E
E
L
E
V
Y
G
S
E
Nematode Worm
Caenorhab. elegans
Q9N4C2
1454
162698
D435
N
D
D
D
E
Q
I
D
E
S
L
Q
F
R
E
Sea Urchin
Strong. purpuratus
XP_789715
1220
135970
W317
L
P
G
C
L
D
M
W
T
V
K
S
L
K
E
Poplar Tree
Populus trichocarpa
XP_002318462
1455
159431
A490
E
L
S
L
Y
S
S
A
P
N
N
A
E
S
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGR0
1442
158057
P493
L
S
L
F
G
S
T
P
N
N
S
D
S
A
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SEY2
1456
158155
G465
E
G
D
S
V
L
L
G
W
T
R
R
Q
G
Q
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
90.8
N.A.
96.5
92.8
N.A.
50.6
N.A.
N.A.
79.6
N.A.
46.7
54.3
31.5
47.6
Protein Similarity:
100
N.A.
N.A.
92.5
N.A.
98
94.3
N.A.
53.3
N.A.
N.A.
89.2
N.A.
65.5
71
52.2
60.7
P-Site Identity:
100
N.A.
N.A.
0
N.A.
0
6.6
N.A.
0
N.A.
N.A.
93.3
N.A.
0
6.6
13.3
0
P-Site Similarity:
100
N.A.
N.A.
6.6
N.A.
6.6
20
N.A.
0
N.A.
N.A.
100
N.A.
13.3
13.3
33.3
40
Percent
Protein Identity:
33.1
N.A.
N.A.
32.8
N.A.
28
Protein Similarity:
51.6
N.A.
N.A.
51.8
N.A.
48.7
P-Site Identity:
20
N.A.
N.A.
0
N.A.
20
P-Site Similarity:
40
N.A.
N.A.
13.3
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
8
8
0
16
24
0
8
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
31
31
8
8
8
0
8
0
0
8
8
0
0
0
% D
% Glu:
39
0
24
16
24
16
8
16
8
31
16
8
16
0
31
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
8
8
0
8
8
0
24
16
0
0
8
8
24
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
16
16
0
8
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
8
0
0
0
0
0
8
0
0
8
0
% K
% Leu:
24
16
8
8
8
8
8
0
8
0
8
0
8
8
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
8
16
8
0
0
0
0
% N
% Pro:
8
8
0
0
0
8
0
8
8
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
8
0
0
0
8
0
24
24
8
16
% Q
% Arg:
0
0
0
0
0
0
8
8
0
0
8
8
0
8
0
% R
% Ser:
0
8
8
8
0
24
16
0
16
24
16
8
24
31
8
% S
% Thr:
0
8
0
0
0
0
8
0
8
8
0
0
8
0
16
% T
% Val:
16
8
0
8
8
16
16
0
0
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
16
0
16
16
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _