KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF1
All Species:
16.97
Human Site:
Y19
Identified Species:
31.11
UniProt:
Q10570
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q10570
NP_037423.2
1443
160884
Y19
T
G
L
E
F
S
M
Y
C
N
F
F
N
N
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532356
1499
165986
G77
S
A
S
A
R
E
R
G
P
Q
H
S
E
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPU4
1441
160800
Y19
T
G
L
E
F
T
M
Y
C
N
F
F
N
N
S
Rat
Rattus norvegicus
NP_001124043
1386
154862
Y19
T
G
L
E
F
A
M
Y
C
N
F
F
N
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514888
831
91833
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108153
1449
162918
Y19
T
A
V
E
F
A
V
Y
C
N
F
I
S
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V726
1455
164663
R21
V
E
F
S
I
A
C
R
F
F
N
N
L
D
E
Honey Bee
Apis mellifera
XP_624382
1415
160872
T19
T
G
V
E
H
A
I
T
C
Y
F
F
N
R
S
Nematode Worm
Caenorhab. elegans
Q9N4C2
1454
162698
G20
A
I
N
F
S
A
Y
G
K
F
L
P
G
E
N
Sea Urchin
Strong. purpuratus
XP_789715
1220
135970
Poplar Tree
Populus trichocarpa
XP_002318462
1455
159431
T58
H
G
G
G
I
G
P
T
P
N
L
I
V
A
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGR0
1442
158057
V61
I
G
P
L
P
N
V
V
I
T
A
A
N
I
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SEY2
1456
158155
Q25
T
L
Q
L
V
P
G
Q
G
T
N
L
A
V
A
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
90.8
N.A.
96.5
92.8
N.A.
50.6
N.A.
N.A.
79.6
N.A.
46.7
54.3
31.5
47.6
Protein Similarity:
100
N.A.
N.A.
92.5
N.A.
98
94.3
N.A.
53.3
N.A.
N.A.
89.2
N.A.
65.5
71
52.2
60.7
P-Site Identity:
100
N.A.
N.A.
6.6
N.A.
93.3
93.3
N.A.
0
N.A.
N.A.
46.6
N.A.
0
53.3
0
0
P-Site Similarity:
100
N.A.
N.A.
13.3
N.A.
100
100
N.A.
0
N.A.
N.A.
80
N.A.
13.3
73.3
13.3
0
Percent
Protein Identity:
33.1
N.A.
N.A.
32.8
N.A.
28
Protein Similarity:
51.6
N.A.
N.A.
51.8
N.A.
48.7
P-Site Identity:
20
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
20
N.A.
N.A.
26.6
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
0
8
0
39
0
0
0
0
8
8
8
8
8
% A
% Cys:
0
0
0
0
0
0
8
0
39
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
8
0
39
0
8
0
0
0
0
0
0
8
8
8
% E
% Phe:
0
0
8
8
31
0
0
0
8
16
39
31
0
0
0
% F
% Gly:
0
47
8
8
0
8
8
16
8
0
0
0
8
8
0
% G
% His:
8
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
8
8
0
0
16
0
8
0
8
0
0
16
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
0
8
24
16
0
0
0
0
0
0
16
8
8
0
8
% L
% Met:
0
0
0
0
0
0
24
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
8
0
0
0
39
16
8
39
24
8
% N
% Pro:
0
0
8
0
8
8
8
0
16
0
0
8
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
8
0
8
0
0
0
0
8
% Q
% Arg:
0
0
0
0
8
0
8
8
0
0
0
0
0
8
0
% R
% Ser:
8
0
8
8
8
8
0
0
0
0
0
8
8
8
47
% S
% Thr:
47
0
0
0
0
8
0
16
0
16
0
0
0
0
0
% T
% Val:
8
0
16
0
8
0
16
8
0
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
31
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _