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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF1
All Species:
15.15
Human Site:
Y1236
Identified Species:
27.78
UniProt:
Q10570
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q10570
NP_037423.2
1443
160884
Y1236
K
S
I
S
L
L
R
Y
Q
E
E
S
K
T
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532356
1499
165986
Y1292
K
S
I
S
L
L
R
Y
Q
E
E
S
K
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPU4
1441
160800
Y1234
K
S
I
S
L
L
R
Y
Q
E
E
S
K
T
L
Rat
Rattus norvegicus
NP_001124043
1386
154862
K1184
L
R
Y
Q
E
E
S
K
T
L
S
L
V
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514888
831
91833
R639
K
N
F
P
M
G
Q
R
V
L
V
D
S
S
F
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108153
1449
162918
Y1242
K
S
I
S
L
L
R
Y
Q
P
E
S
K
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V726
1455
164663
F1249
K
S
I
S
L
L
R
F
Q
E
E
Y
R
T
L
Honey Bee
Apis mellifera
XP_624382
1415
160872
F1207
K
S
I
S
L
L
R
F
Q
E
E
Y
R
T
L
Nematode Worm
Caenorhab. elegans
Q9N4C2
1454
162698
F1242
E
S
M
S
L
I
R
F
Q
E
D
N
K
A
M
Sea Urchin
Strong. purpuratus
XP_789715
1220
135970
P1028
L
V
S
R
D
A
R
P
L
E
I
F
G
C
E
Poplar Tree
Populus trichocarpa
XP_002318462
1455
159431
W1246
K
S
I
Y
F
L
S
W
K
E
Q
G
A
Q
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGR0
1442
158057
W1242
K
S
I
Y
F
L
S
W
K
E
Q
G
S
Q
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SEY2
1456
158155
Y1229
K
G
V
W
F
T
G
Y
T
E
E
P
Y
K
M
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
90.8
N.A.
96.5
92.8
N.A.
50.6
N.A.
N.A.
79.6
N.A.
46.7
54.3
31.5
47.6
Protein Similarity:
100
N.A.
N.A.
92.5
N.A.
98
94.3
N.A.
53.3
N.A.
N.A.
89.2
N.A.
65.5
71
52.2
60.7
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
0
N.A.
6.6
N.A.
N.A.
93.3
N.A.
80
80
46.6
13.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
6.6
N.A.
33.3
N.A.
N.A.
93.3
N.A.
93.3
93.3
93.3
13.3
Percent
Protein Identity:
33.1
N.A.
N.A.
32.8
N.A.
28
Protein Similarity:
51.6
N.A.
N.A.
51.8
N.A.
48.7
P-Site Identity:
40
N.A.
N.A.
40
N.A.
26.6
P-Site Similarity:
60
N.A.
N.A.
60
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
0
0
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
8
8
0
0
0
% D
% Glu:
8
0
0
0
8
8
0
0
0
77
54
0
0
0
8
% E
% Phe:
0
0
8
0
24
0
0
24
0
0
0
8
0
0
8
% F
% Gly:
0
8
0
0
0
8
8
0
0
0
0
16
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
62
0
0
8
0
0
0
0
8
0
0
0
0
% I
% Lys:
77
0
0
0
0
0
0
8
16
0
0
0
39
8
0
% K
% Leu:
16
0
0
0
54
62
0
0
8
16
0
8
0
0
62
% L
% Met:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
16
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
8
0
8
0
8
0
0
0
% P
% Gln:
0
0
0
8
0
0
8
0
54
0
16
0
0
16
0
% Q
% Arg:
0
8
0
8
0
0
62
8
0
0
0
0
16
0
8
% R
% Ser:
0
70
8
54
0
0
24
0
0
0
8
31
16
16
0
% S
% Thr:
0
0
0
0
0
8
0
0
16
0
0
0
0
47
0
% T
% Val:
0
8
8
0
0
0
0
0
8
0
8
0
8
0
0
% V
% Trp:
0
0
0
8
0
0
0
16
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
16
0
0
0
39
0
0
0
16
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _