KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF1
All Species:
20.3
Human Site:
Y1164
Identified Species:
37.22
UniProt:
Q10570
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q10570
NP_037423.2
1443
160884
Y1164
K
N
K
F
K
V
L
Y
E
K
E
Q
K
G
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532356
1499
165986
Y1220
K
N
K
F
K
V
L
Y
E
K
E
Q
K
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPU4
1441
160800
Y1162
K
N
K
F
K
V
L
Y
E
K
E
Q
K
G
P
Rat
Rattus norvegicus
NP_001124043
1386
154862
K1112
E
E
T
V
S
G
L
K
G
Y
V
A
A
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514888
831
91833
E567
S
H
T
V
D
D
E
E
E
M
L
Y
G
D
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108153
1449
162918
Y1170
K
N
K
F
K
V
L
Y
E
K
E
Q
K
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V726
1455
164663
F1177
K
F
K
I
K
E
I
F
K
K
E
Q
K
G
P
Honey Bee
Apis mellifera
XP_624382
1415
160872
Y1135
K
N
R
F
K
Q
I
Y
A
K
E
Q
K
G
P
Nematode Worm
Caenorhab. elegans
Q9N4C2
1454
162698
F1170
N
R
K
I
K
V
L
F
D
K
E
Q
K
G
P
Sea Urchin
Strong. purpuratus
XP_789715
1220
135970
G956
S
A
L
C
E
V
M
G
F
L
L
T
C
I
G
Poplar Tree
Populus trichocarpa
XP_002318462
1455
159431
S1174
I
L
V
S
E
V
Y
S
K
E
L
K
G
A
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGR0
1442
158057
S1170
N
V
V
T
E
V
Y
S
R
E
L
K
G
A
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SEY2
1456
158155
R1157
V
A
K
E
D
I
P
R
G
A
V
T
A
L
S
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
90.8
N.A.
96.5
92.8
N.A.
50.6
N.A.
N.A.
79.6
N.A.
46.7
54.3
31.5
47.6
Protein Similarity:
100
N.A.
N.A.
92.5
N.A.
98
94.3
N.A.
53.3
N.A.
N.A.
89.2
N.A.
65.5
71
52.2
60.7
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
13.3
N.A.
6.6
N.A.
N.A.
100
N.A.
60
73.3
66.6
6.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
20
N.A.
13.3
N.A.
N.A.
100
N.A.
80
86.6
80
20
Percent
Protein Identity:
33.1
N.A.
N.A.
32.8
N.A.
28
Protein Similarity:
51.6
N.A.
N.A.
51.8
N.A.
48.7
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
33.3
N.A.
N.A.
26.6
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
0
0
0
8
8
0
8
16
16
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
16
8
0
0
8
0
0
0
0
8
0
% D
% Glu:
8
8
0
8
24
8
8
8
39
16
54
0
0
0
0
% E
% Phe:
0
8
0
39
0
0
0
16
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
8
16
0
0
0
24
62
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
16
0
8
16
0
0
0
0
0
0
8
16
% I
% Lys:
47
0
54
0
54
0
0
8
16
54
0
16
54
0
0
% K
% Leu:
0
8
8
0
0
0
47
0
0
8
31
0
0
8
0
% L
% Met:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% M
% Asn:
16
39
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
54
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
54
0
0
0
% Q
% Arg:
0
8
8
0
0
0
0
8
8
0
0
0
0
0
0
% R
% Ser:
16
0
0
8
8
0
0
16
0
0
0
0
0
0
16
% S
% Thr:
0
0
16
8
0
0
0
0
0
0
0
16
0
0
8
% T
% Val:
8
8
16
16
0
62
0
0
0
0
16
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
16
39
0
8
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _