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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF1
All Species:
13.03
Human Site:
Y1066
Identified Species:
23.89
UniProt:
Q10570
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q10570
NP_037423.2
1443
160884
Y1066
T
I
E
R
D
E
R
Y
I
H
P
Q
Q
E
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532356
1499
165986
Y1122
T
I
E
R
D
D
R
Y
I
H
P
Q
Q
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPU4
1441
160800
Y1064
A
I
E
R
D
D
R
Y
I
H
P
Q
Q
E
A
Rat
Rattus norvegicus
NP_001124043
1386
154862
V1023
A
H
Y
V
A
Y
H
V
E
S
K
V
Y
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514888
831
91833
V479
C
A
V
A
D
P
Y
V
V
I
M
S
A
E
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108153
1449
162918
Y1072
T
I
E
R
D
E
R
Y
I
H
P
Q
Q
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V726
1455
164663
F1079
E
E
S
R
G
E
R
F
I
Y
P
I
G
S
Q
Honey Bee
Apis mellifera
XP_624382
1415
160872
F1037
E
E
E
R
P
D
R
F
I
F
P
S
Q
E
Q
Nematode Worm
Caenorhab. elegans
Q9N4C2
1454
162698
F1072
I
H
E
K
D
E
N
F
V
L
P
A
P
P
K
Sea Urchin
Strong. purpuratus
XP_789715
1220
135970
I868
D
A
I
P
N
T
R
I
E
Y
E
A
A
E
N
Poplar Tree
Populus trichocarpa
XP_002318462
1455
159431
N1074
G
H
Q
I
E
N
H
N
L
S
S
E
E
I
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGR0
1442
158057
N1068
G
Q
Q
L
D
N
H
N
M
S
S
D
D
L
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SEY2
1456
158155
P1058
R
E
N
I
T
F
K
P
M
V
D
R
G
V
L
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
90.8
N.A.
96.5
92.8
N.A.
50.6
N.A.
N.A.
79.6
N.A.
46.7
54.3
31.5
47.6
Protein Similarity:
100
N.A.
N.A.
92.5
N.A.
98
94.3
N.A.
53.3
N.A.
N.A.
89.2
N.A.
65.5
71
52.2
60.7
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
86.6
0
N.A.
13.3
N.A.
N.A.
86.6
N.A.
33.3
46.6
26.6
13.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
93.3
0
N.A.
20
N.A.
N.A.
93.3
N.A.
46.6
60
46.6
26.6
Percent
Protein Identity:
33.1
N.A.
N.A.
32.8
N.A.
28
Protein Similarity:
51.6
N.A.
N.A.
51.8
N.A.
48.7
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
33.3
N.A.
N.A.
20
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
16
0
8
8
0
0
0
0
0
0
16
16
8
24
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
54
24
0
0
0
0
8
8
8
8
0
% D
% Glu:
16
24
47
0
8
31
0
0
16
0
8
8
8
47
0
% E
% Phe:
0
0
0
0
0
8
0
24
0
8
0
0
0
0
0
% F
% Gly:
16
0
0
0
8
0
0
0
0
0
0
0
16
0
8
% G
% His:
0
24
0
0
0
0
24
0
0
31
0
0
0
0
8
% H
% Ile:
8
31
8
16
0
0
0
8
47
8
0
8
0
8
0
% I
% Lys:
0
0
0
8
0
0
8
0
0
0
8
0
0
0
16
% K
% Leu:
0
0
0
8
0
0
0
0
8
8
0
0
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
16
0
8
0
0
0
0
% M
% Asn:
0
0
8
0
8
16
8
16
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
8
8
8
0
8
0
0
54
0
8
8
0
% P
% Gln:
0
8
16
0
0
0
0
0
0
0
0
31
39
0
24
% Q
% Arg:
8
0
0
47
0
0
54
0
0
0
0
8
0
0
0
% R
% Ser:
0
0
8
0
0
0
0
0
0
24
16
16
0
8
0
% S
% Thr:
24
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
8
8
0
0
0
16
16
8
0
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
8
8
31
0
16
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _