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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF1
All Species:
16.36
Human Site:
T1105
Identified Species:
30
UniProt:
Q10570
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q10570
NP_037423.2
1443
160884
T1105
E
H
V
T
C
M
K
T
V
S
L
R
S
E
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532356
1499
165986
T1161
E
H
V
T
C
M
K
T
V
S
L
R
S
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPU4
1441
160800
T1103
E
H
V
T
C
M
K
T
V
S
L
R
S
E
E
Rat
Rattus norvegicus
NP_001124043
1386
154862
Y1060
A
I
E
R
D
D
R
Y
I
H
P
Q
Q
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514888
831
91833
Q515
H
K
P
P
L
H
S
Q
S
K
V
I
A
L
C
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108153
1449
162918
T1111
E
H
V
T
C
M
K
T
V
A
L
K
S
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V726
1455
164663
I1118
E
H
V
T
A
F
K
I
V
K
L
S
Y
E
G
Honey Bee
Apis mellifera
XP_624382
1415
160872
N1076
E
H
V
T
C
L
K
N
V
S
L
A
Y
E
G
Nematode Worm
Caenorhab. elegans
Q9N4C2
1454
162698
D1111
E
A
V
T
A
C
E
D
V
A
L
K
S
E
S
Sea Urchin
Strong. purpuratus
XP_789715
1220
135970
V904
V
V
V
A
T
T
H
V
Y
S
E
D
L
Q
T
Poplar Tree
Populus trichocarpa
XP_002318462
1455
159431
R1119
S
E
N
A
L
T
V
R
M
V
S
L
F
N
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGR0
1442
158057
R1115
S
E
H
A
L
T
V
R
V
V
T
L
L
N
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SEY2
1456
158155
S1098
E
T
L
N
L
E
V
S
E
S
T
N
E
R
K
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
90.8
N.A.
96.5
92.8
N.A.
50.6
N.A.
N.A.
79.6
N.A.
46.7
54.3
31.5
47.6
Protein Similarity:
100
N.A.
N.A.
92.5
N.A.
98
94.3
N.A.
53.3
N.A.
N.A.
89.2
N.A.
65.5
71
52.2
60.7
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
6.6
N.A.
0
N.A.
N.A.
80
N.A.
53.3
66.6
46.6
13.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
26.6
N.A.
13.3
N.A.
N.A.
100
N.A.
53.3
73.3
66.6
20
Percent
Protein Identity:
33.1
N.A.
N.A.
32.8
N.A.
28
Protein Similarity:
51.6
N.A.
N.A.
51.8
N.A.
48.7
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
6.6
N.A.
N.A.
6.6
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
24
16
0
0
0
0
16
0
8
8
0
16
% A
% Cys:
0
0
0
0
39
8
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
8
8
0
8
0
0
0
8
0
0
0
% D
% Glu:
62
16
8
0
0
8
8
0
8
0
8
0
8
54
31
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% G
% His:
8
47
8
0
0
8
8
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
8
8
0
0
8
0
0
0
% I
% Lys:
0
8
0
0
0
0
47
0
0
16
0
16
0
0
8
% K
% Leu:
0
0
8
0
31
8
0
0
0
0
54
16
16
8
0
% L
% Met:
0
0
0
0
0
31
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
0
0
8
0
0
0
8
0
16
0
% N
% Pro:
0
0
8
8
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
8
8
16
0
% Q
% Arg:
0
0
0
8
0
0
8
16
0
0
0
24
0
8
0
% R
% Ser:
16
0
0
0
0
0
8
8
8
47
8
8
39
0
8
% S
% Thr:
0
8
0
54
8
24
0
31
0
0
16
0
0
0
16
% T
% Val:
8
8
62
0
0
0
24
8
62
16
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
8
0
0
0
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _