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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C2orf77 All Species: 13.33
Human Site: S538 Identified Species: 29.33
UniProt: Q0VFZ6 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q0VFZ6 NP_001078916.1 546 65752 S538 P K Y N F Q K S K R R L G F T
Chimpanzee Pan troglodytes XP_001134856 644 75715 S636 P K Y N F Q K S K R R L G F T
Rhesus Macaque Macaca mulatta XP_001098455 435 52096 S427 P K Y N F Q K S K R R L G F T
Dog Lupus familis XP_535951 367 44109 A349 E K E K K R K A D K K H R E V
Cat Felis silvestris
Mouse Mus musculus A0JLY1 547 65114 K538 S K Y N D F Q K S K R R L G F
Rat Rattus norvegicus NP_001120958 546 65273 S538 S K Y D F Q K S K R R L G F T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514040 532 63813 K523 A T R G D F Q K S K R R L G F
Chicken Gallus gallus XP_422007 1141 129633 E915 A K Q E N K R E G E K I Q R L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002663472 551 64813 N535 T Q N I K E L N E T S D I Q Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VAY7 359 42838 K352 S Y D K Y T I K D K D K S K K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787312 560 65635 H545 T D E V K Y A H I G K P S N T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.5 77.6 54 N.A. 75.1 75.8 N.A. 53.1 21.8 N.A. 37 N.A. 21.7 N.A. N.A. 37.5
Protein Similarity: 100 84.6 78.5 59.5 N.A. 88.1 88.6 N.A. 75 34.7 N.A. 62.2 N.A. 38.6 N.A. N.A. 61
P-Site Identity: 100 100 100 13.3 N.A. 26.6 86.6 N.A. 6.6 6.6 N.A. 0 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 100 100 40 N.A. 40 93.3 N.A. 20 33.3 N.A. 26.6 N.A. 13.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 10 10 19 0 0 0 19 0 10 10 0 0 0 % D
% Glu: 10 0 19 10 0 10 0 10 10 10 0 0 0 10 0 % E
% Phe: 0 0 0 0 37 19 0 0 0 0 0 0 0 37 19 % F
% Gly: 0 0 0 10 0 0 0 0 10 10 0 0 37 19 0 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % H
% Ile: 0 0 0 10 0 0 10 0 10 0 0 10 10 0 0 % I
% Lys: 0 64 0 19 28 10 46 28 37 37 28 10 0 10 10 % K
% Leu: 0 0 0 0 0 0 10 0 0 0 0 37 19 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 37 10 0 0 10 0 0 0 0 0 10 0 % N
% Pro: 28 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % P
% Gln: 0 10 10 0 0 37 19 0 0 0 0 0 10 10 10 % Q
% Arg: 0 0 10 0 0 10 10 0 0 37 55 19 10 10 0 % R
% Ser: 28 0 0 0 0 0 0 37 19 0 10 0 19 0 0 % S
% Thr: 19 10 0 0 0 10 0 0 0 10 0 0 0 0 46 % T
% Val: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 46 0 10 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _