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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASGEF1B
All Species:
16.97
Human Site:
Y448
Identified Species:
46.67
UniProt:
Q0VAM2
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q0VAM2
NP_689758.1
473
55359
Y448
D
A
L
Y
L
A
S
Y
E
S
E
G
P
E
N
Chimpanzee
Pan troglodytes
XP_001153731
467
53007
Y442
D
G
L
Y
L
A
S
Y
E
S
E
S
P
E
N
Rhesus Macaque
Macaca mulatta
XP_001084596
560
64388
P514
D
A
C
S
P
Q
C
P
L
D
D
Q
P
L
R
Dog
Lupus familis
XP_848924
466
54546
E440
L
T
V
P
V
F
S
E
D
A
L
Y
L
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZL7
473
55255
Y448
D
A
L
Y
L
A
S
Y
E
S
E
G
P
E
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507622
522
60072
F497
E
A
L
F
V
A
S
F
E
S
E
G
P
E
N
Chicken
Gallus gallus
XP_414615
480
55173
Y455
D
G
L
Y
L
A
S
Y
E
S
E
S
P
E
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DHR3
514
59871
Y489
D
A
L
Y
L
A
S
Y
E
S
E
G
P
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789261
598
68657
V569
N
Y
L
L
T
A
P
V
F
S
E
N
S
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.4
76
97
N.A.
97.4
N.A.
N.A.
56.3
70
N.A.
78.7
N.A.
N.A.
N.A.
N.A.
47.1
Protein Similarity:
100
77.3
77.6
98.3
N.A.
99.3
N.A.
N.A.
72.4
82.7
N.A.
86.3
N.A.
N.A.
N.A.
N.A.
62
P-Site Identity:
100
86.6
20
6.6
N.A.
100
N.A.
N.A.
73.3
86.6
N.A.
100
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
86.6
26.6
40
N.A.
100
N.A.
N.A.
100
86.6
N.A.
100
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
56
0
0
0
78
0
0
0
12
0
0
0
12
0
% A
% Cys:
0
0
12
0
0
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
67
0
0
0
0
0
0
0
12
12
12
0
0
0
0
% D
% Glu:
12
0
0
0
0
0
0
12
67
0
78
0
0
67
0
% E
% Phe:
0
0
0
12
0
12
0
12
12
0
0
0
0
0
0
% F
% Gly:
0
23
0
0
0
0
0
0
0
0
0
45
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
12
0
78
12
56
0
0
0
12
0
12
0
12
23
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
0
0
0
12
0
0
78
% N
% Pro:
0
0
0
12
12
0
12
12
0
0
0
0
78
0
0
% P
% Gln:
0
0
0
0
0
12
0
0
0
0
0
12
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% R
% Ser:
0
0
0
12
0
0
78
0
0
78
0
23
12
0
12
% S
% Thr:
0
12
0
0
12
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
12
0
23
0
0
12
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
56
0
0
0
56
0
0
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _