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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NSUN2
All Species:
27.27
Human Site:
Y612
Identified Species:
50
UniProt:
Q08J23
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08J23
NP_060225.4
767
86471
Y612
Q
E
G
I
Y
T
L
Y
P
F
I
N
S
R
I
Chimpanzee
Pan troglodytes
XP_517620
767
86455
Y612
Q
E
G
I
Y
T
L
Y
P
F
I
N
S
R
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535800
780
87547
Y614
Q
E
G
I
Y
T
L
Y
P
F
I
N
S
R
I
Cat
Felis silvestris
Mouse
Mus musculus
Q1HFZ0
757
85433
Y611
Q
E
G
I
Y
T
L
Y
P
F
I
N
S
R
I
Rat
Rattus norvegicus
NP_001101873
782
88072
Y636
Q
E
G
I
Y
T
L
Y
P
F
I
N
S
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521204
837
94743
Y655
Q
E
G
I
Y
T
L
Y
P
F
I
N
S
R
I
Chicken
Gallus gallus
Q5ZLV4
796
90826
Y608
Q
E
G
I
Y
T
L
Y
P
F
I
H
A
R
I
Frog
Xenopus laevis
Q4V7N2
698
80033
V557
K
K
R
Q
L
Y
M
V
S
K
E
L
R
N
V
Zebra Danio
Brachydanio rerio
NP_956005
706
79550
C548
Q
E
G
V
Y
T
L
C
P
Y
I
R
A
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4M9
746
84143
M586
L
Q
T
S
N
A
F
M
G
A
S
R
R
I
Q
Honey Bee
Apis mellifera
XP_395050
725
83777
I578
Q
E
G
I
Q
I
I
I
K
Y
I
G
N
S
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850024
808
89794
F664
A
S
V
G
L
K
M
F
E
R
Q
S
A
K
E
Baker's Yeast
Sacchar. cerevisiae
P38205
684
77860
E544
C
S
W
R
I
Q
S
E
S
L
P
I
M
K
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
85.9
N.A.
86.8
84.1
N.A.
72.4
72.3
69.4
65.1
N.A.
43.5
42.3
N.A.
N.A.
Protein Similarity:
100
99.6
N.A.
90.1
N.A.
90.7
88.6
N.A.
78.3
80.1
78.8
73.4
N.A.
60
60.8
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
86.6
0
66.6
N.A.
0
33.3
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
26.6
86.6
N.A.
6.6
53.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.3
34.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45
52.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
0
0
8
0
0
24
0
0
% A
% Cys:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
70
0
0
0
0
0
8
8
0
8
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
8
8
0
54
0
0
0
0
0
% F
% Gly:
0
0
70
8
0
0
0
0
8
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% H
% Ile:
0
0
0
62
8
8
8
8
0
0
70
8
0
8
62
% I
% Lys:
8
8
0
0
0
8
0
0
8
8
0
0
0
16
0
% K
% Leu:
8
0
0
0
16
0
62
0
0
8
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
16
8
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
47
8
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
62
0
8
0
0
0
0
% P
% Gln:
70
8
0
8
8
8
0
0
0
0
8
0
0
0
8
% Q
% Arg:
0
0
8
8
0
0
0
0
0
8
0
16
16
62
8
% R
% Ser:
0
16
0
8
0
0
8
0
16
0
8
8
47
8
0
% S
% Thr:
0
0
8
0
0
62
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
8
8
0
0
0
8
0
0
0
0
0
0
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
62
8
0
54
0
16
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _