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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NSUN2
All Species:
6.97
Human Site:
S721
Identified Species:
12.78
UniProt:
Q08J23
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08J23
NP_060225.4
767
86471
S721
G
V
I
L
T
N
E
S
A
A
S
T
G
Q
P
Chimpanzee
Pan troglodytes
XP_517620
767
86455
S721
G
V
I
L
T
N
E
S
A
A
S
T
G
Q
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535800
780
87547
S723
G
T
S
L
A
Q
E
S
T
G
S
S
G
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q1HFZ0
757
85433
L716
K
K
K
E
G
V
I
L
T
N
E
N
A
A
S
Rat
Rattus norvegicus
NP_001101873
782
88072
I740
E
K
K
K
E
G
V
I
L
T
N
E
S
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521204
837
94743
N766
P
E
N
K
A
E
E
N
Q
A
T
T
G
P
A
Chicken
Gallus gallus
Q5ZLV4
796
90826
E737
G
M
D
V
E
D
K
E
R
D
A
V
T
K
M
Frog
Xenopus laevis
Q4V7N2
698
80033
P657
S
I
V
L
K
Y
E
P
D
P
Q
Q
P
E
T
Zebra Danio
Brachydanio rerio
NP_956005
706
79550
D664
T
Q
E
E
S
T
E
D
A
E
G
L
S
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4M9
746
84143
A692
D
A
R
V
A
A
A
A
A
A
D
A
E
V
G
Honey Bee
Apis mellifera
XP_395050
725
83777
E684
F
E
K
N
K
F
K
E
N
R
A
S
A
A
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850024
808
89794
A766
W
R
G
K
A
S
L
A
V
M
A
T
V
A
D
Baker's Yeast
Sacchar. cerevisiae
P38205
684
77860
F643
H
E
L
L
Y
R
I
F
G
I
D
A
N
A
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
85.9
N.A.
86.8
84.1
N.A.
72.4
72.3
69.4
65.1
N.A.
43.5
42.3
N.A.
N.A.
Protein Similarity:
100
99.6
N.A.
90.1
N.A.
90.7
88.6
N.A.
78.3
80.1
78.8
73.4
N.A.
60
60.8
N.A.
N.A.
P-Site Identity:
100
100
N.A.
46.6
N.A.
0
0
N.A.
26.6
6.6
13.3
20
N.A.
13.3
0
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
53.3
N.A.
0
6.6
N.A.
40
46.6
33.3
26.6
N.A.
26.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.3
34.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45
52.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
31
8
8
16
31
31
24
16
16
31
24
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
8
0
8
8
8
16
0
0
0
8
% D
% Glu:
8
24
8
16
16
8
47
16
0
8
8
8
8
8
8
% E
% Phe:
8
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% F
% Gly:
31
0
8
0
8
8
0
0
8
8
8
0
31
0
8
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
16
0
0
0
16
8
0
8
0
0
0
0
0
% I
% Lys:
8
16
24
24
16
0
16
0
0
0
0
0
0
8
8
% K
% Leu:
0
0
8
39
0
0
8
8
8
0
0
8
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
8
% M
% Asn:
0
0
8
8
0
16
0
8
8
8
8
8
8
0
0
% N
% Pro:
8
0
0
0
0
0
0
8
0
8
0
0
8
16
24
% P
% Gln:
0
8
0
0
0
8
0
0
8
0
8
8
0
24
0
% Q
% Arg:
0
8
8
0
0
8
0
0
8
8
0
0
0
0
0
% R
% Ser:
8
0
8
0
8
8
0
24
0
0
24
16
16
0
8
% S
% Thr:
8
8
0
0
16
8
0
0
16
8
8
31
8
0
8
% T
% Val:
0
16
8
16
0
8
8
0
8
0
0
8
8
16
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _