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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NSUN2
All Species:
21.52
Human Site:
S593
Identified Species:
39.44
UniProt:
Q08J23
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08J23
NP_060225.4
767
86471
S593
K
V
W
C
R
N
N
S
G
E
E
F
D
C
A
Chimpanzee
Pan troglodytes
XP_517620
767
86455
S593
K
V
W
C
R
N
N
S
G
E
E
F
D
C
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535800
780
87547
S595
K
V
W
C
R
N
N
S
G
E
E
F
D
C
A
Cat
Felis silvestris
Mouse
Mus musculus
Q1HFZ0
757
85433
S592
K
V
W
C
R
N
N
S
G
E
E
F
D
C
A
Rat
Rattus norvegicus
NP_001101873
782
88072
S617
K
V
W
C
R
N
N
S
G
E
E
F
D
C
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521204
837
94743
D636
K
V
W
S
R
N
N
D
G
E
Q
F
G
C
A
Chicken
Gallus gallus
Q5ZLV4
796
90826
D589
K
V
W
S
R
N
S
D
G
E
Q
F
G
C
A
Frog
Xenopus laevis
Q4V7N2
698
80033
K539
A
L
D
P
S
F
P
K
K
N
L
L
T
R
T
Zebra Danio
Brachydanio rerio
NP_956005
706
79550
D529
K
V
L
S
R
N
N
D
G
E
Q
F
G
C
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4M9
746
84143
T568
V
R
C
E
N
R
H
T
V
H
P
F
R
L
A
Honey Bee
Apis mellifera
XP_395050
725
83777
N560
K
S
F
V
R
C
D
N
K
N
M
D
C
P
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850024
808
89794
S639
R
I
Y
Y
V
S
K
S
V
K
E
V
L
Q
L
Baker's Yeast
Sacchar. cerevisiae
P38205
684
77860
K526
K
I
I
Y
S
G
V
K
L
F
V
S
Q
R
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
85.9
N.A.
86.8
84.1
N.A.
72.4
72.3
69.4
65.1
N.A.
43.5
42.3
N.A.
N.A.
Protein Similarity:
100
99.6
N.A.
90.1
N.A.
90.7
88.6
N.A.
78.3
80.1
78.8
73.4
N.A.
60
60.8
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
73.3
66.6
0
66.6
N.A.
13.3
13.3
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
80
80
6.6
73.3
N.A.
26.6
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.3
34.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45
52.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
70
% A
% Cys:
0
0
8
39
0
8
0
0
0
0
0
0
8
62
0
% C
% Asp:
0
0
8
0
0
0
8
24
0
0
0
8
39
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
62
47
0
0
0
0
% E
% Phe:
0
0
8
0
0
8
0
0
0
8
0
70
0
0
8
% F
% Gly:
0
0
0
0
0
8
0
0
62
0
0
0
24
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
0
16
8
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
77
0
0
0
0
0
8
16
16
8
0
0
0
0
0
% K
% Leu:
0
8
8
0
0
0
0
0
8
0
8
8
8
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
8
62
54
8
0
16
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
8
0
0
0
8
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
24
0
8
8
0
% Q
% Arg:
8
8
0
0
70
8
0
0
0
0
0
0
8
16
0
% R
% Ser:
0
8
0
24
16
8
8
47
0
0
0
8
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
8
% T
% Val:
8
62
0
8
8
0
8
0
16
0
8
8
0
0
0
% V
% Trp:
0
0
54
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
16
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _