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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFGE8
All Species:
31.52
Human Site:
S249
Identified Species:
69.33
UniProt:
Q08431
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08431
NP_001108086.1
387
43123
S249
P
D
K
Q
I
T
A
S
S
S
Y
K
T
W
G
Chimpanzee
Pan troglodytes
XP_001165789
387
43145
S249
P
D
K
Q
I
T
A
S
S
S
Y
K
T
W
G
Rhesus Macaque
Macaca mulatta
XP_001082401
470
52704
S328
Q
D
Y
Q
I
T
A
S
S
V
F
R
T
L
N
Dog
Lupus familis
XP_545848
688
74486
S293
P
D
K
Q
I
T
A
S
S
I
Y
R
T
W
G
Cat
Felis silvestris
Mouse
Mus musculus
P21956
463
51250
S327
P
D
S
Q
M
S
A
S
S
S
Y
K
T
W
N
Rat
Rattus norvegicus
P70490
427
47394
S291
P
D
S
Q
I
T
A
S
S
S
Y
K
T
W
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511628
535
59319
E401
R
M
E
L
L
G
C
E
L
S
G
C
S
E
P
Chicken
Gallus gallus
XP_413867
474
53128
S334
S
D
Q
Q
I
T
A
S
S
V
F
K
T
W
G
Frog
Xenopus laevis
NP_001089989
469
52138
S329
S
D
K
Q
I
K
A
S
S
V
F
K
T
W
G
Zebra Danio
Brachydanio rerio
NP_001074459
473
52317
S333
S
D
R
Q
M
T
S
S
S
A
F
R
T
W
G
Tiger Blowfish
Takifugu rubipres
Q9W6R5
280
32014
A157
S
S
W
L
P
S
K
A
R
L
N
T
Q
G
F
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
43.4
35.9
N.A.
53.1
56.6
N.A.
37
46.4
45.8
46
27.9
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
56.3
43
N.A.
63.9
68.6
N.A.
46.3
59.9
58
60
41
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
53.3
86.6
N.A.
73.3
86.6
N.A.
6.6
73.3
73.3
53.3
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
66.6
93.3
N.A.
86.6
86.6
N.A.
26.6
86.6
80
93.3
13.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
73
10
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% C
% Asp:
0
82
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
10
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
37
0
0
0
10
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
10
0
0
10
55
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
64
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
37
0
0
10
10
0
0
0
0
55
0
0
0
% K
% Leu:
0
0
0
19
10
0
0
0
10
10
0
0
0
10
0
% L
% Met:
0
10
0
0
19
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
28
% N
% Pro:
46
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
10
0
10
82
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
10
0
10
0
0
0
0
0
10
0
0
28
0
0
0
% R
% Ser:
37
10
19
0
0
19
10
82
82
46
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
64
0
0
0
0
0
10
82
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
28
0
0
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
73
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
46
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _