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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EHHADH All Species: 17.58
Human Site: S354 Identified Species: 48.33
UniProt: Q08426 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q08426 NP_001957.2 723 79495 S354 E A S K M Q Q S G H P W S G P
Chimpanzee Pan troglodytes XP_517004 723 79481 S354 E A S K M Q Q S G H P W S G P
Rhesus Macaque Macaca mulatta XP_001096204 723 79327 S354 E A S K M Q Q S G H P W S G P
Dog Lupus familis XP_545234 723 79611 S354 E A S K M Q R S S H P S L G P
Cat Felis silvestris
Mouse Mus musculus Q9DBM2 718 78225 A352 E A S K S G Q A S A K P N L R
Rat Rattus norvegicus P07896 722 78639 N353 E A S R A H Q N G Q A S A K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512869 696 76686 S327 E A S K M Q K S G Q S W A A P
Chicken Gallus gallus XP_422690 726 79645 G354 E A M K M E Q G A Q T L D F H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NYL3 718 78490 S352 D A K R R G V S A S L N L L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 95.9 86 N.A. 77.8 77.7 N.A. 72.1 63 N.A. 55 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 97.9 92.9 N.A. 88.5 89 N.A. 84.5 79 N.A. 70.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 73.3 N.A. 33.3 40 N.A. 66.6 33.3 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 80 N.A. 46.6 60 N.A. 80 40 N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 100 0 0 12 0 0 12 23 12 12 0 23 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % D
% Glu: 89 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % F
% Gly: 0 0 0 0 0 23 0 12 56 0 0 0 0 45 0 % G
% His: 0 0 0 0 0 12 0 0 0 45 0 0 0 0 12 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 12 78 0 0 12 0 0 0 12 0 0 12 12 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 12 12 23 23 0 % L
% Met: 0 0 12 0 67 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 12 0 0 0 12 12 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 45 12 0 0 67 % P
% Gln: 0 0 0 0 0 56 67 0 0 34 0 0 0 0 0 % Q
% Arg: 0 0 0 23 12 0 12 0 0 0 0 0 0 0 12 % R
% Ser: 0 0 78 0 12 0 0 67 23 12 12 23 34 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % T
% Val: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 45 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _