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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRYZ
All Species:
36.97
Human Site:
T259
Identified Species:
73.94
UniProt:
Q08257
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08257
NP_001123514.1
329
35207
T259
I
E
I
N
P
R
D
T
M
A
K
E
S
S
I
Chimpanzee
Pan troglodytes
XP_513498
329
35213
T259
I
E
I
N
P
R
D
T
M
A
K
E
S
S
I
Rhesus Macaque
Macaca mulatta
XP_001100174
329
35223
T259
I
E
I
N
P
R
D
T
M
A
K
E
S
S
I
Dog
Lupus familis
XP_853797
330
35503
T259
I
E
I
N
P
R
D
T
I
P
K
E
T
S
I
Cat
Felis silvestris
Mouse
Mus musculus
P47199
331
35250
T261
I
E
I
N
P
R
D
T
M
A
K
E
T
S
I
Rat
Rattus norvegicus
Q6AYT0
329
34957
T259
I
E
I
N
P
R
D
T
M
A
K
E
T
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506108
340
35937
T270
V
E
I
N
P
R
D
T
M
V
K
E
S
S
I
Chicken
Gallus gallus
NP_001073231
331
35308
T261
I
E
I
N
P
R
D
T
M
N
K
E
S
S
I
Frog
Xenopus laevis
NP_001086430
329
35056
T259
I
E
I
N
P
R
D
T
M
A
K
E
T
S
I
Zebra Danio
Brachydanio rerio
Q8JFV8
484
53544
T326
N
L
F
A
V
A
K
T
W
Y
Q
Q
F
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6U9
357
39093
I284
G
P
L
I
F
K
D
I
A
F
R
G
F
W
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_493577
328
35401
L256
T
T
I
N
A
R
Q
L
M
V
T
E
G
A
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.9
86.3
N.A.
80.6
80.8
N.A.
80
69.4
66.8
22.5
N.A.
25.2
N.A.
41
N.A.
Protein Similarity:
100
99.6
99
92.7
N.A.
90.3
90.2
N.A.
88.5
82.4
84.1
38
N.A.
43.4
N.A.
61.4
N.A.
P-Site Identity:
100
100
100
80
N.A.
93.3
93.3
N.A.
86.6
93.3
93.3
13.3
N.A.
6.6
N.A.
33.3
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
93.3
93.3
100
33.3
N.A.
33.3
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
9
0
0
9
50
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
84
0
0
0
0
0
0
0
0
% D
% Glu:
0
75
0
0
0
0
0
0
0
0
0
84
0
0
0
% E
% Phe:
0
0
9
0
9
0
0
0
0
9
0
0
17
0
0
% F
% Gly:
9
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
67
0
84
9
0
0
0
9
9
0
0
0
0
0
75
% I
% Lys:
0
0
0
0
0
9
9
0
0
0
75
0
0
0
0
% K
% Leu:
0
9
9
0
0
0
0
9
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
75
0
0
0
0
0
9
% M
% Asn:
9
0
0
84
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
9
0
0
75
0
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
9
9
0
0
0
% Q
% Arg:
0
0
0
0
0
84
0
0
0
0
9
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
42
84
0
% S
% Thr:
9
9
0
0
0
0
0
84
0
0
9
0
34
0
0
% T
% Val:
9
0
0
0
9
0
0
0
0
17
0
0
0
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _