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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SFRS4
All Species:
12.42
Human Site:
T436
Identified Species:
22.78
UniProt:
Q08170
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08170
NP_005617.2
494
56678
T436
G
E
S
E
N
A
G
T
N
Q
E
T
R
S
R
Chimpanzee
Pan troglodytes
Q5R1W5
221
25469
R164
S
R
S
T
S
K
S
R
S
A
R
R
S
K
S
Rhesus Macaque
Macaca mulatta
XP_001113540
494
56669
T436
G
E
S
E
N
A
G
T
N
Q
E
T
R
S
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE97
489
55961
P431
A
E
G
E
S
E
A
P
N
P
E
P
R
A
R
Rat
Rattus norvegicus
Q09167
269
30873
S212
S
R
R
S
K
S
Y
S
R
S
R
S
R
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512981
401
44678
K343
R
D
A
K
P
D
G
K
K
R
K
K
D
D
A
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079647
667
76917
T506
D
R
S
G
S
R
S
T
S
K
Q
E
R
S
N
Zebra Danio
Brachydanio rerio
Q6NYA0
245
27457
Y188
S
H
E
G
E
T
A
Y
I
R
V
K
V
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26686
376
42795
P319
H
R
D
S
R
S
R
P
P
T
V
S
F
K
S
Honey Bee
Apis mellifera
XP_391860
342
39488
S285
K
S
K
S
K
S
R
S
R
S
R
S
K
A
E
Nematode Worm
Caenorhab. elegans
Q23120
281
32403
K224
G
S
D
R
S
D
R
K
S
R
S
A
S
P
K
Sea Urchin
Strong. purpuratus
XP_798746
311
35431
S254
K
S
R
S
R
S
K
S
P
R
K
S
P
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22315
303
33711
A246
K
S
S
R
R
S
P
A
K
S
T
S
R
S
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.5
99.1
N.A.
N.A.
87.2
39.8
N.A.
63.3
N.A.
52
22.6
N.A.
49.3
36.2
32.5
34.6
Protein Similarity:
100
33.2
99.5
N.A.
N.A.
90.2
46.1
N.A.
70.8
N.A.
61.4
29.3
N.A.
57.4
48.9
42.3
44.9
P-Site Identity:
100
6.6
100
N.A.
N.A.
40
20
N.A.
6.6
N.A.
26.6
0
N.A.
0
0
6.6
6.6
P-Site Similarity:
100
20
100
N.A.
N.A.
53.3
40
N.A.
40
N.A.
53.3
6.6
N.A.
13.3
33.3
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
16
16
8
0
8
0
8
0
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
16
0
0
16
0
0
0
0
0
0
8
16
0
% D
% Glu:
0
24
8
24
8
8
0
0
0
0
24
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
24
0
8
16
0
0
24
0
0
0
0
0
0
0
8
% G
% His:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
24
0
8
8
16
8
8
16
16
8
16
16
8
24
8
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
16
0
0
0
24
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
8
0
8
16
16
8
0
8
8
8
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
16
8
0
0
0
0
% Q
% Arg:
8
31
16
16
24
8
24
8
16
31
24
8
47
0
39
% R
% Ser:
24
31
39
31
31
39
16
24
24
24
8
39
16
39
16
% S
% Thr:
0
0
0
8
0
8
0
24
0
8
8
16
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
16
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _