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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS4 All Species: 10.91
Human Site: S391 Identified Species: 20
UniProt: Q08170 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.42
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q08170 NP_005617.2 494 56678 S391 R D S K A G S S K K K K K E D
Chimpanzee Pan troglodytes Q5R1W5 221 25469 S119 G G G Y G R R S R S P R R R R
Rhesus Macaque Macaca mulatta XP_001113540 494 56669 S391 R D S K A G S S K K K K K E D
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8VE97 489 55961 S386 R D S K V S S S S S S S K K K
Rat Rattus norvegicus Q09167 269 30873 K167 A I E K L S G K E I N G R K I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512981 401 44678 R298 S V S K A R S R S R S G S K D
Chicken Gallus gallus
Frog Xenopus laevis NP_001079647 667 76917 S461 S K D E M S L S R S R E N R E
Zebra Danio Brachydanio rerio Q6NYA0 245 27457 A143 L K D H M R E A G D V C Y A D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P26686 376 42795 K274 D V S K S K S K S H S R T R S
Honey Bee Apis mellifera XP_391860 342 39488 R240 S R S R R S S R S K S R A H T
Nematode Worm Caenorhab. elegans Q23120 281 32403 L179 E D L N G R K L K C T D E T R
Sea Urchin Strong. purpuratus XP_798746 311 35431 R209 P S S S S R R R S R S H S R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22315 303 33711 S201 E Y D S R K D S R S P S R G R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 27.5 99.1 N.A. N.A. 87.2 39.8 N.A. 63.3 N.A. 52 22.6 N.A. 49.3 36.2 32.5 34.6
Protein Similarity: 100 33.2 99.5 N.A. N.A. 90.2 46.1 N.A. 70.8 N.A. 61.4 29.3 N.A. 57.4 48.9 42.3 44.9
P-Site Identity: 100 6.6 100 N.A. N.A. 46.6 6.6 N.A. 33.3 N.A. 6.6 6.6 N.A. 20 20 13.3 6.6
P-Site Similarity: 100 26.6 100 N.A. N.A. 53.3 26.6 N.A. 46.6 N.A. 40 13.3 N.A. 33.3 33.3 20 20
Percent
Protein Identity: N.A. N.A. N.A. 26.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 35.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 24 0 0 8 0 0 0 0 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % C
% Asp: 8 31 24 0 0 0 8 0 0 8 0 8 0 0 31 % D
% Glu: 16 0 8 8 0 0 8 0 8 0 0 8 8 16 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 8 8 0 16 16 8 0 8 0 0 16 0 8 0 % G
% His: 0 0 0 8 0 0 0 0 0 8 0 8 0 8 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 8 0 0 0 0 8 % I
% Lys: 0 16 0 47 0 16 8 16 24 24 16 16 24 24 8 % K
% Leu: 8 0 8 0 8 0 8 8 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 16 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 0 8 0 8 0 0 % N
% Pro: 8 0 0 0 0 0 0 0 0 0 16 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 24 8 0 8 16 39 16 24 24 16 8 24 24 31 24 % R
% Ser: 24 8 54 16 16 31 47 47 39 31 39 16 16 0 16 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 8 0 8 8 8 % T
% Val: 0 16 0 0 8 0 0 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 8 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _