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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS4 All Species: 9.09
Human Site: S249 Identified Species: 16.67
UniProt: Q08170 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q08170 NP_005617.2 494 56678 S249 S K K E K S R S P S K E K S R
Chimpanzee Pan troglodytes Q5R1W5 221 25469
Rhesus Macaque Macaca mulatta XP_001113540 494 56669 S249 S K K E K S R S P S K D K S R
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8VE97 489 55961 S247 S R S K K E K S R S P S K D N
Rat Rattus norvegicus Q09167 269 30873 R29 R F F K G Y G R I R D I D L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512981 401 44678 G159 R L V E D R P G S R R R R S Y
Chicken Gallus gallus
Frog Xenopus laevis NP_001079647 667 76917 S267 L H G S Q S R S I S R G K Q D
Zebra Danio Brachydanio rerio Q6NYA0 245 27457
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P26686 376 42795 L136 S R V S W Q D L K D Y M R Q A
Honey Bee Apis mellifera XP_391860 342 39488 N102 R R S A V N R N T R T A S S Y
Nematode Worm Caenorhab. elegans Q23120 281 32403 V40 M K N G F G F V D F Q D Q R D
Sea Urchin Strong. purpuratus XP_798746 311 35431 H71 G E R V I I E H A R G P A R G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22315 303 33711 H63 R D A E D A I H G R D G Y D F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 27.5 99.1 N.A. N.A. 87.2 39.8 N.A. 63.3 N.A. 52 22.6 N.A. 49.3 36.2 32.5 34.6
Protein Similarity: 100 33.2 99.5 N.A. N.A. 90.2 46.1 N.A. 70.8 N.A. 61.4 29.3 N.A. 57.4 48.9 42.3 44.9
P-Site Identity: 100 0 93.3 N.A. N.A. 33.3 0 N.A. 13.3 N.A. 33.3 0 N.A. 6.6 13.3 6.6 0
P-Site Similarity: 100 0 100 N.A. N.A. 53.3 13.3 N.A. 26.6 N.A. 46.6 0 N.A. 20 33.3 26.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. 26.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 35.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 8 0 0 8 0 0 8 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 16 0 8 0 8 8 16 16 8 16 16 % D
% Glu: 0 8 0 31 0 8 8 0 0 0 0 8 0 0 0 % E
% Phe: 0 8 8 0 8 0 8 0 0 8 0 0 0 0 8 % F
% Gly: 8 0 8 8 8 8 8 8 8 0 8 16 0 0 8 % G
% His: 0 8 0 0 0 0 0 16 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 8 8 0 16 0 0 8 0 0 0 % I
% Lys: 0 24 16 16 24 0 8 0 8 0 16 0 31 0 8 % K
% Leu: 8 8 0 0 0 0 0 8 0 0 0 0 0 8 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 8 0 0 8 0 8 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 0 8 0 16 0 8 8 0 0 0 % P
% Gln: 0 0 0 0 8 8 0 0 0 0 8 0 8 16 0 % Q
% Arg: 31 24 8 0 0 8 31 8 8 39 16 8 16 16 16 % R
% Ser: 31 0 16 16 0 24 0 31 8 31 0 8 8 31 0 % S
% Thr: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % T
% Val: 0 0 16 8 8 0 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 8 0 8 0 16 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _