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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS4 All Species: 11.52
Human Site: S224 Identified Species: 21.11
UniProt: Q08170 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q08170 NP_005617.2 494 56678 S224 K S R S R S R S G S R S R S K
Chimpanzee Pan troglodytes Q5R1W5 221 25469
Rhesus Macaque Macaca mulatta XP_001113540 494 56669 S224 K S R S R S R S G S R S R S K
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8VE97 489 55961 S222 H S K S R S R S R S G S H S R
Rat Rattus norvegicus Q09167 269 30873
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512981 401 44678 M134 E F V S Y S D M K R A L E K L
Chicken Gallus gallus
Frog Xenopus laevis NP_001079647 667 76917 S242 Q S P G K S Q S R S R S R S R
Zebra Danio Brachydanio rerio Q6NYA0 245 27457
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P26686 376 42795 R111 K N S R S S S R Y G P P L R T
Honey Bee Apis mellifera XP_391860 342 39488 R77 E R A R G T P R G S D Q W R Y
Nematode Worm Caenorhab. elegans Q23120 281 32403 D15 R L P N R A S D R D V E H F F
Sea Urchin Strong. purpuratus XP_798746 311 35431 D46 F G F V E F E D Y R D A D D A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22315 303 33711 L38 G P V V Q I D L K V P P R P P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 27.5 99.1 N.A. N.A. 87.2 39.8 N.A. 63.3 N.A. 52 22.6 N.A. 49.3 36.2 32.5 34.6
Protein Similarity: 100 33.2 99.5 N.A. N.A. 90.2 46.1 N.A. 70.8 N.A. 61.4 29.3 N.A. 57.4 48.9 42.3 44.9
P-Site Identity: 100 0 100 N.A. N.A. 60 0 N.A. 13.3 N.A. 53.3 0 N.A. 13.3 13.3 6.6 0
P-Site Similarity: 100 0 100 N.A. N.A. 73.3 0 N.A. 20 N.A. 80 0 N.A. 20 26.6 26.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. 26.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 35.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 8 0 0 0 0 8 8 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 16 16 0 8 16 0 8 8 0 % D
% Glu: 16 0 0 0 8 0 8 0 0 0 0 8 8 0 0 % E
% Phe: 8 8 8 0 0 8 0 0 0 0 0 0 0 8 8 % F
% Gly: 8 8 0 8 8 0 0 0 24 8 8 0 0 0 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 16 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 24 0 8 0 8 0 0 0 16 0 0 0 0 8 16 % K
% Leu: 0 8 0 0 0 0 0 8 0 0 0 8 8 0 8 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 8 16 0 0 0 8 0 0 0 16 16 0 8 8 % P
% Gln: 8 0 0 0 8 0 8 0 0 0 0 8 0 0 0 % Q
% Arg: 8 8 16 16 31 0 24 16 24 16 24 0 31 16 16 % R
% Ser: 0 31 8 31 8 47 16 31 0 39 0 31 0 31 0 % S
% Thr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % T
% Val: 0 0 16 16 0 0 0 0 0 8 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 16 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _