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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACTN3 All Species: 36.06
Human Site: S370 Identified Species: 99.17
UniProt: Q08043 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q08043 NP_001095.1 901 103241 S370 H R P A F M P S E G K L V S D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001109839 901 103277 S370 H R P A F M P S E G K L V S D
Dog Lupus familis XP_852336 901 103273 S370 H R P A F M P S E G K L V S D
Cat Felis silvestris
Mouse Mus musculus O88990 900 103024 S369 H R P A F M P S E G K L V S D
Rat Rattus norvegicus Q9Z1P2 892 102942 S356 N R P A F M P S E G R M V S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P20111 897 104257 S366 N R P A F M P S E G K M V S D
Frog Xenopus laevis NP_001086492 896 103580 S365 N R P A F M P S E G K M V S D
Zebra Danio Brachydanio rerio NP_571597 896 103549 S365 N R P A F M P S E G K M V S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P18091 924 107001 T388 N R P A Y L P T E G K T V S D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.6 96.7 N.A. 97.1 76.4 N.A. N.A. 78.5 82.6 81.6 N.A. 66.5 N.A. N.A. N.A.
Protein Similarity: 100 N.A. 99.3 98.5 N.A. 98.4 88.5 N.A. N.A. 89.5 91.9 91.4 N.A. 81 N.A. N.A. N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 100 80 N.A. N.A. 86.6 86.6 86.6 N.A. 66.6 N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 93.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % D
% Glu: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 89 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % G
% His: 45 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 89 0 0 0 0 % K
% Leu: 0 0 0 0 0 12 0 0 0 0 0 45 0 0 0 % L
% Met: 0 0 0 0 0 89 0 0 0 0 0 45 0 0 0 % M
% Asn: 56 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 100 0 0 0 100 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 100 0 0 0 0 0 0 0 0 12 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 89 0 0 0 0 0 100 0 % S
% Thr: 0 0 0 0 0 0 0 12 0 0 0 12 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _