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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPAG1
All Species:
22.12
Human Site:
Y646
Identified Species:
40.56
UniProt:
Q07617
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07617
NP_003105.2
926
103639
Y646
Y
K
D
A
L
S
K
Y
S
E
C
L
K
I
N
Chimpanzee
Pan troglodytes
XP_001151756
925
103559
Y645
Y
K
D
A
L
S
K
Y
S
E
C
L
K
I
N
Rhesus Macaque
Macaca mulatta
XP_001097243
934
104557
Y653
Y
K
D
A
L
R
K
Y
S
E
C
L
K
I
N
Dog
Lupus familis
XP_848730
421
47825
Y173
T
V
V
N
N
K
S
Y
L
S
K
I
E
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80ZX8
901
100651
Y629
Y
K
D
A
I
S
K
Y
N
E
C
L
K
I
N
Rat
Rattus norvegicus
Q5U2X2
893
100597
Y628
Y
K
D
A
I
S
K
Y
N
E
C
L
K
I
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506694
365
42180
P117
E
E
S
Q
I
Q
H
P
K
T
G
A
F
Q
E
Chicken
Gallus gallus
Q5ZKQ3
665
75976
S417
P
A
V
L
I
K
E
S
E
I
K
N
I
V
K
Frog
Xenopus laevis
Q6NU95
660
75087
S412
D
R
N
G
N
K
D
S
N
Q
R
K
L
I
N
Zebra Danio
Brachydanio rerio
NP_001082875
386
42425
K138
N
R
A
A
C
F
L
K
D
G
N
S
A
D
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651514
469
53806
S221
Q
A
Q
L
K
N
L
S
Q
L
E
K
E
Q
F
Honey Bee
Apis mellifera
XP_394942
579
66433
G331
T
N
A
V
A
I
A
G
V
K
K
L
R
K
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P15705
589
66247
R341
V
I
S
K
S
F
A
R
I
G
N
A
Y
H
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95
34.8
N.A.
68.9
67.7
N.A.
29.9
24.1
23.6
24.8
N.A.
21.8
20.7
N.A.
N.A.
Protein Similarity:
100
99.4
96.5
39.8
N.A.
79.3
77.7
N.A.
34.5
39.8
38.9
31.4
N.A.
35.3
37
N.A.
N.A.
P-Site Identity:
100
100
93.3
6.6
N.A.
86.6
86.6
N.A.
0
0
13.3
6.6
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
100
93.3
20
N.A.
100
100
N.A.
13.3
20
40
13.3
N.A.
13.3
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
16
47
8
0
16
0
0
0
0
16
8
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
39
0
0
0
8
% C
% Asp:
8
0
39
0
0
0
8
0
8
0
0
0
0
8
0
% D
% Glu:
8
8
0
0
0
0
8
0
8
39
8
0
16
0
8
% E
% Phe:
0
0
0
0
0
16
0
0
0
0
0
0
8
0
8
% F
% Gly:
0
0
0
8
0
0
0
8
0
16
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
0
0
31
8
0
0
8
8
0
8
8
47
0
% I
% Lys:
0
39
0
8
8
24
39
8
8
8
24
16
39
8
16
% K
% Leu:
0
0
0
16
24
0
16
0
8
8
0
47
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
8
8
16
8
0
0
24
0
16
8
0
0
47
% N
% Pro:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% P
% Gln:
8
0
8
8
0
8
0
0
8
8
0
0
0
16
0
% Q
% Arg:
0
16
0
0
0
8
0
8
0
0
8
0
8
0
8
% R
% Ser:
0
0
16
0
8
31
8
24
24
8
0
8
0
0
0
% S
% Thr:
16
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% T
% Val:
8
8
16
8
0
0
0
0
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
39
0
0
0
0
0
0
47
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _