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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPAG1 All Species: 5.45
Human Site: T433 Identified Species: 10
UniProt: Q07617 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q07617 NP_003105.2 926 103639 T433 A A A G G G A T G H P G G G Q
Chimpanzee Pan troglodytes XP_001151756 925 103559 H434 A G G G A T G H P G G G Q G A
Rhesus Macaque Macaca mulatta XP_001097243 934 104557 T434 A A A G G G A T G H P G G R P
Dog Lupus familis XP_848730 421 47825
Cat Felis silvestris
Mouse Mus musculus Q80ZX8 901 100651 Y420 A S T G D S H Y P E E P R A A
Rat Rattus norvegicus Q5U2X2 893 100597 D419 A S T S D N H D L E E R R A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506694 365 42180
Chicken Gallus gallus Q5ZKQ3 665 75976 A210 A Y A R R G A A R F A L K N F
Frog Xenopus laevis Q6NU95 660 75087 R205 D Y A K A Y A R R G A A R L A
Zebra Danio Brachydanio rerio NP_001082875 386 42425
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651514 469 53806 N14 K S L L E R Y N I P I H Y L D
Honey Bee Apis mellifera XP_394942 579 66433 T124 D L E E G K T T L L N P L P S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P15705 589 66247 Q134 Q P D L G L T Q L F A D P N L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 95 34.8 N.A. 68.9 67.7 N.A. 29.9 24.1 23.6 24.8 N.A. 21.8 20.7 N.A. N.A.
Protein Similarity: 100 99.4 96.5 39.8 N.A. 79.3 77.7 N.A. 34.5 39.8 38.9 31.4 N.A. 35.3 37 N.A. N.A.
P-Site Identity: 100 26.6 86.6 0 N.A. 13.3 6.6 N.A. 0 26.6 13.3 0 N.A. 0 13.3 N.A. N.A.
P-Site Similarity: 100 26.6 86.6 0 N.A. 20 13.3 N.A. 0 26.6 13.3 0 N.A. 6.6 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 33.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 47 16 31 0 16 0 31 8 0 0 24 8 0 16 31 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 16 0 8 0 16 0 0 8 0 0 0 8 0 0 8 % D
% Glu: 0 0 8 8 8 0 0 0 0 16 16 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 16 0 0 0 0 8 % F
% Gly: 0 8 8 31 31 24 8 0 16 16 8 24 16 16 0 % G
% His: 0 0 0 0 0 0 16 8 0 16 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % I
% Lys: 8 0 0 8 0 8 0 0 0 0 0 0 8 0 0 % K
% Leu: 0 8 8 16 0 8 0 0 24 8 0 8 8 16 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 8 0 0 8 0 0 16 0 % N
% Pro: 0 8 0 0 0 0 0 0 16 8 16 16 8 8 8 % P
% Gln: 8 0 0 0 0 0 0 8 0 0 0 0 8 0 8 % Q
% Arg: 0 0 0 8 8 8 0 8 16 0 0 8 24 8 0 % R
% Ser: 0 24 0 8 0 8 0 0 0 0 0 0 0 0 8 % S
% Thr: 0 0 16 0 0 8 16 24 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 16 0 0 0 8 8 8 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _