Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPAG1 All Species: 17.88
Human Site: S817 Identified Species: 32.78
UniProt: Q07617 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q07617 NP_003105.2 926 103639 S817 G Q I I N A L S T R K D K E A
Chimpanzee Pan troglodytes XP_001151756 925 103559 S816 G Q I I N A L S T R K D K E A
Rhesus Macaque Macaca mulatta XP_001097243 934 104557 S825 G Q I I N A L S T R K D K E A
Dog Lupus familis XP_848730 421 47825 Y313 L L R R A T T Y K H Q N K L Q
Cat Felis silvestris
Mouse Mus musculus Q80ZX8 901 100651 S792 G Q V L S T I S A R K D E E A
Rat Rattus norvegicus Q5U2X2 893 100597 S784 G Q V L S T I S A R K D E E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506694 365 42180 Q257 A Q A A I K L Q N W N S V F Q
Chicken Gallus gallus Q5ZKQ3 665 75976 L557 L E S D F R K L K D C P E K M
Frog Xenopus laevis Q6NU95 660 75087 R552 F Q L E S D F R R L K G N P D
Zebra Danio Brachydanio rerio NP_001082875 386 42425 Q278 L V K N S Q F Q G A S E K Y S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651514 469 53806 I361 T R L I I E E I D P P Q L K T
Honey Bee Apis mellifera XP_394942 579 66433 H471 P D P L T A K H K S T F S R T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P15705 589 66247 A481 Q I A V K E Y A S A L E T L D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 95 34.8 N.A. 68.9 67.7 N.A. 29.9 24.1 23.6 24.8 N.A. 21.8 20.7 N.A. N.A.
Protein Similarity: 100 99.4 96.5 39.8 N.A. 79.3 77.7 N.A. 34.5 39.8 38.9 31.4 N.A. 35.3 37 N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 53.3 53.3 N.A. 13.3 0 13.3 6.6 N.A. 6.6 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 20 N.A. 86.6 86.6 N.A. 13.3 20 26.6 26.6 N.A. 26.6 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 33.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 16 8 8 31 0 8 16 16 0 0 0 0 39 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 8 0 8 0 8 0 0 8 8 0 39 0 0 16 % D
% Glu: 0 8 0 8 0 16 8 0 0 0 0 16 24 39 0 % E
% Phe: 8 0 0 0 8 0 16 0 0 0 0 8 0 8 0 % F
% Gly: 39 0 0 0 0 0 0 0 8 0 0 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % H
% Ile: 0 8 24 31 16 0 16 8 0 0 0 0 0 0 0 % I
% Lys: 0 0 8 0 8 8 16 0 24 0 47 0 39 16 0 % K
% Leu: 24 8 16 24 0 0 31 8 0 8 8 0 8 16 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 8 24 0 0 0 8 0 8 8 8 0 0 % N
% Pro: 8 0 8 0 0 0 0 0 0 8 8 8 0 8 0 % P
% Gln: 8 54 0 0 0 8 0 16 0 0 8 8 0 0 16 % Q
% Arg: 0 8 8 8 0 8 0 8 8 39 0 0 0 8 0 % R
% Ser: 0 0 8 0 31 0 0 39 8 8 8 8 8 0 8 % S
% Thr: 8 0 0 0 8 24 8 0 24 0 8 0 8 0 16 % T
% Val: 0 8 16 8 0 0 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 8 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _