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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGF All Species: 25.45
Human Site: S72 Identified Species: 46.67
UniProt: Q07326 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q07326 NP_002634.1 219 24890 S72 N T S S K R S S L S H K V T G
Chimpanzee Pan troglodytes XP_001147889 219 24970 S72 N T S S K R S S L S H K V T R
Rhesus Macaque Macaca mulatta XP_001113130 219 24899 S72 N T S S K R S S L S H K V T R
Dog Lupus familis XP_531809 219 25180 S72 N A S S K R S S I S Y K V T R
Cat Felis silvestris
Mouse Mus musculus O09101 219 24806 S72 N V S S K R S S L S H K V T R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508401 403 43802 G127 Q G P A P N G G G S G Q V S R
Chicken Gallus gallus
Frog Xenopus laevis NP_001088813 219 24617 S72 N A S S K K S S L A N K F N K
Zebra Danio Brachydanio rerio NP_991208 219 24392 T72 S P P T K K N T L S Y K I S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001187877 166 17772 H34 F F S S I A F H I V A V L Y G
Poplar Tree Populus trichocarpa XP_002303863 230 25414 Q83 R F R I D P Q Q C S Y L K A V
Maize Zea mays NP_001131399 218 23446 L79 F R A V A R G L I G L P V G A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06636 219 25243 N70 V F V S S N F N T V K L L S F
Red Bread Mold Neurospora crassa Q871U9 272 28468 S119 P A A G E P A S K S N R K P R
Conservation
Percent
Protein Identity: 100 99.5 97.2 92.6 N.A. 87.6 N.A. N.A. 28.5 N.A. 63 52.9 N.A. N.A. N.A. N.A. 34.7
Protein Similarity: 100 99.5 98.1 95.4 N.A. 92.2 N.A. N.A. 38.2 N.A. 81.2 75.8 N.A. N.A. N.A. N.A. 46.5
P-Site Identity: 100 93.3 93.3 73.3 N.A. 86.6 N.A. N.A. 13.3 N.A. 53.3 26.6 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 93.3 93.3 86.6 N.A. 86.6 N.A. N.A. 33.3 N.A. 73.3 80 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: 25.6 29.6 N.A. N.A. 21.9 24.2
Protein Similarity: 44.7 49.3 N.A. N.A. 38.3 38.9
P-Site Identity: 6.6 13.3 N.A. N.A. 6.6 13.3
P-Site Similarity: 13.3 26.6 N.A. N.A. 26.6 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 24 16 8 8 8 8 0 0 8 8 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 16 24 0 0 0 0 16 0 0 0 0 0 8 0 8 % F
% Gly: 0 8 0 8 0 0 16 8 8 8 8 0 0 8 16 % G
% His: 0 0 0 0 0 0 0 8 0 0 31 0 0 0 0 % H
% Ile: 0 0 0 8 8 0 0 0 24 0 0 0 8 0 0 % I
% Lys: 0 0 0 0 54 16 0 0 8 0 8 54 16 0 8 % K
% Leu: 0 0 0 0 0 0 0 8 47 0 8 16 16 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 47 0 0 0 0 16 8 8 0 0 16 0 0 8 0 % N
% Pro: 8 8 16 0 8 16 0 0 0 0 0 8 0 8 0 % P
% Gln: 8 0 0 0 0 0 8 8 0 0 0 8 0 0 0 % Q
% Arg: 8 8 8 0 0 47 0 0 0 0 0 8 0 0 54 % R
% Ser: 8 0 54 62 8 0 47 54 0 70 0 0 0 24 0 % S
% Thr: 0 24 0 8 0 0 0 8 8 0 0 0 0 39 0 % T
% Val: 8 8 8 8 0 0 0 0 0 16 0 8 54 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 24 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _