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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENPEP
All Species:
26.97
Human Site:
Y253
Identified Species:
65.93
UniProt:
Q07075
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07075
NP_001968.3
957
109272
Y253
S
I
T
H
P
K
E
Y
G
A
L
S
N
M
P
Chimpanzee
Pan troglodytes
XP_517397
957
109097
Y253
S
I
T
H
P
K
E
Y
G
A
L
S
N
M
P
Rhesus Macaque
Macaca mulatta
XP_001090456
957
109170
Y253
S
I
T
H
P
K
E
Y
E
A
L
S
N
M
P
Dog
Lupus familis
XP_535696
954
109183
Y250
S
I
I
H
P
K
E
Y
K
A
V
S
N
M
P
Cat
Felis silvestris
Mouse
Mus musculus
P16406
945
107938
Y245
S
I
I
H
P
K
E
Y
S
A
L
S
N
M
P
Rat
Rattus norvegicus
P50123
945
107977
Y245
S
L
I
H
P
K
E
Y
S
A
L
S
N
M
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506613
933
106738
S241
P
P
S
Y
S
A
L
S
N
M
P
V
E
K
I
Chicken
Gallus gallus
XP_426327
940
107525
Y241
S
I
I
H
Q
D
T
Y
G
A
L
S
N
M
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_731787
1025
116367
Y308
A
R
P
S
G
D
E
Y
H
V
L
S
N
M
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37898
856
97644
R171
H
L
S
N
M
D
V
R
N
E
T
I
K
E
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.5
82.9
N.A.
77.5
78.1
N.A.
71.1
66.8
N.A.
N.A.
N.A.
37.3
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98.5
90.5
N.A.
87.8
88
N.A.
82
79.4
N.A.
N.A.
N.A.
56.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
86.6
80
N.A.
0
73.3
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
86.6
86.6
N.A.
13.3
73.3
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
0
0
70
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
30
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
70
0
10
10
0
0
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
30
0
0
0
0
0
10
% G
% His:
10
0
0
70
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
60
40
0
0
0
0
0
0
0
0
10
0
0
10
% I
% Lys:
0
0
0
0
0
60
0
0
10
0
0
0
10
10
0
% K
% Leu:
0
20
0
0
0
0
10
0
0
0
70
0
0
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
10
0
0
0
80
0
% M
% Asn:
0
0
0
10
0
0
0
0
20
0
0
0
80
0
0
% N
% Pro:
10
10
10
0
60
0
0
0
0
0
10
0
0
0
80
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
70
0
20
10
10
0
0
10
20
0
0
80
0
0
0
% S
% Thr:
0
0
30
0
0
0
10
0
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
10
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _