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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAX8
All Species:
13.94
Human Site:
T166
Identified Species:
30.67
UniProt:
Q06710
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06710
NP_003457.1
450
48218
T166
L
I
P
S
S
A
V
T
P
P
E
S
P
Q
S
Chimpanzee
Pan troglodytes
Q2VL62
341
36320
R59
C
V
S
K
I
L
A
R
Y
N
E
T
G
S
I
Rhesus Macaque
Macaca mulatta
Q2VL61
341
36390
R59
C
V
S
K
I
L
A
R
Y
N
E
T
G
S
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q00288
457
48833
T166
L
I
P
S
S
A
V
T
P
P
E
S
P
Q
S
Rat
Rattus norvegicus
P51974
457
48788
T166
L
I
P
S
S
A
V
T
P
P
E
S
P
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513168
422
46031
R136
P
S
V
S
S
I
N
R
L
P
R
L
R
A
S
Chicken
Gallus gallus
P55166
339
36196
R57
C
V
S
K
I
L
A
R
Y
N
E
T
G
S
I
Frog
Xenopus laevis
Q9PUK5
465
49555
T181
L
I
P
S
S
T
V
T
P
P
E
S
P
H
S
Zebra Danio
Brachydanio rerio
Q90268
410
44081
C127
R
L
L
A
E
G
V
C
D
N
D
T
V
P
S
Tiger Blowfish
Takifugu rubipres
NP_001032960
424
45219
R139
S
S
I
N
R
I
I
R
T
K
V
Q
Q
Q
P
Fruit Fly
Dros. melanogaster
P06601
613
65479
S184
S
S
C
G
S
D
V
S
G
G
H
H
N
N
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34
34.2
N.A.
N.A.
96.7
96.5
N.A.
48.2
36
73.3
54
46.2
28.2
N.A.
N.A.
N.A.
Protein Similarity:
100
47.7
48
N.A.
N.A.
97.3
97.5
N.A.
58.8
46.8
83
64
58
44.2
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
N.A.
N.A.
100
100
N.A.
26.6
6.6
86.6
13.3
6.6
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
20
N.A.
N.A.
100
100
N.A.
26.6
20
86.6
40
20
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
28
28
0
0
0
0
0
0
10
0
% A
% Cys:
28
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
10
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
64
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
10
0
0
10
10
0
0
28
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
10
0
10
0
% H
% Ile:
0
37
10
0
28
19
10
0
0
0
0
0
0
0
28
% I
% Lys:
0
0
0
28
0
0
0
0
0
10
0
0
0
0
0
% K
% Leu:
37
10
10
0
0
28
0
0
10
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
10
0
0
37
0
0
10
10
0
% N
% Pro:
10
0
37
0
0
0
0
0
37
46
0
0
37
10
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
10
37
0
% Q
% Arg:
10
0
0
0
10
0
0
46
0
0
10
0
10
0
0
% R
% Ser:
19
28
28
46
55
0
0
10
0
0
0
37
0
28
55
% S
% Thr:
0
0
0
0
0
10
0
37
10
0
0
37
0
0
0
% T
% Val:
0
28
10
0
0
0
55
0
0
0
10
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
28
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _