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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPAT All Species: 27.58
Human Site: Y83 Identified Species: 46.67
UniProt: Q06203 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q06203 NP_002694.3 517 57399 Y83 E D N L K K L Y V S N L G I G
Chimpanzee Pan troglodytes XP_001140991 517 57441 Y83 E D N L K K L Y V S N L G I G
Rhesus Macaque Macaca mulatta XP_001085606 517 57427 Y83 E D N L K K L Y V S N L G I G
Dog Lupus familis XP_854170 517 57161 Y83 Q D N L K K L Y I S N L G I G
Cat Felis silvestris
Mouse Mus musculus NP_742158 517 57385 Y83 E D N L K K L Y D S N L G I G
Rat Rattus norvegicus P35433 517 57419 Y83 E D N L K K L Y V S N L G I G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521120 482 53569 C71 G N S E L E N C Q P F V V E T
Chicken Gallus gallus P28173 510 56239 Y83 A D S L K K L Y V S N L G I G
Frog Xenopus laevis NP_001083491 508 55847 H83 E D S L K K L H V S N L G I G
Zebra Danio Brachydanio rerio NP_001076346 508 55199 R83 P E D L L K L R Y G N L G I G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q27601 546 59501 R125 D D S M K K L R G N L G I G H
Honey Bee Apis mellifera XP_396074 525 57582 N107 D E N M K K L N G N L G I G H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780199 520 56746 G106 E I L A N L H G N L G I G H N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P04046 510 56701 S70 R V S G L A G S M G I A H L R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.4 94.1 N.A. 93 93.4 N.A. 81.4 82.4 80.6 73.5 N.A. 56.7 59.4 N.A. 65.1
Protein Similarity: 100 100 100 98 N.A. 96.1 96.7 N.A. 87.6 89.9 90.1 84.3 N.A. 70.8 76.3 N.A. 79
P-Site Identity: 100 100 100 86.6 N.A. 93.3 100 N.A. 0 86.6 86.6 53.3 N.A. 26.6 26.6 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 100 N.A. 26.6 93.3 100 66.6 N.A. 53.3 53.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 31.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 48.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 0 8 0 0 0 0 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 15 65 8 0 0 0 0 0 8 0 0 0 0 0 0 % D
% Glu: 50 15 0 8 0 8 0 0 0 0 0 0 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 8 0 0 8 0 0 8 8 15 15 8 15 72 15 65 % G
% His: 0 0 0 0 0 0 8 8 0 0 0 0 8 8 15 % H
% Ile: 0 8 0 0 0 0 0 0 8 0 8 8 15 65 0 % I
% Lys: 0 0 0 0 72 79 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 8 65 22 8 79 0 0 8 15 65 0 8 0 % L
% Met: 0 0 0 15 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 8 50 0 8 0 8 8 8 15 65 0 0 0 8 % N
% Pro: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Q
% Arg: 8 0 0 0 0 0 0 15 0 0 0 0 0 0 8 % R
% Ser: 0 0 36 0 0 0 0 8 0 58 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % T
% Val: 0 8 0 0 0 0 0 0 43 0 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 50 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _