KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAT
All Species:
22.73
Human Site:
Y157
Identified Species:
38.46
UniProt:
Q06203
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06203
NP_002694.3
517
57399
Y157
M
I
T
Q
L
L
A
Y
T
P
P
Q
E
Q
D
Chimpanzee
Pan troglodytes
XP_001140991
517
57441
Y157
M
I
T
Q
L
L
A
Y
T
P
P
Q
E
Q
D
Rhesus Macaque
Macaca mulatta
XP_001085606
517
57427
Y157
M
I
T
Q
L
L
A
Y
T
P
P
Q
E
Q
D
Dog
Lupus familis
XP_854170
517
57161
Y157
M
I
T
Q
L
L
A
Y
T
P
P
Q
E
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
NP_742158
517
57385
Y157
M
I
T
Q
L
L
A
Y
T
P
P
Q
E
K
D
Rat
Rattus norvegicus
P35433
517
57419
Y157
M
I
T
Q
L
L
A
Y
T
P
P
Q
E
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521120
482
53569
R129
A
Y
T
P
P
L
E
R
D
D
T
P
D
W
V
Chicken
Gallus gallus
P28173
510
56239
F157
L
I
T
Q
L
L
A
F
T
P
P
L
E
N
D
Frog
Xenopus laevis
NP_001083491
508
55847
F157
L
I
T
Q
L
L
A
F
T
P
P
M
E
E
D
Zebra Danio
Brachydanio rerio
NP_001076346
508
55199
L157
L
I
T
Q
L
L
A
L
T
P
P
M
E
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27601
546
59501
C198
L
I
A
Q
S
L
C
C
A
P
E
D
V
S
E
Honey Bee
Apis mellifera
XP_396074
525
57582
L180
L
I
T
Q
A
L
C
L
N
P
P
E
G
E
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780199
520
56746
H178
V
I
T
Q
L
L
T
H
A
P
P
E
G
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P04046
510
56701
N137
S
D
S
E
L
L
L
N
I
F
A
A
E
L
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.4
94.1
N.A.
93
93.4
N.A.
81.4
82.4
80.6
73.5
N.A.
56.7
59.4
N.A.
65.1
Protein Similarity:
100
100
100
98
N.A.
96.1
96.7
N.A.
87.6
89.9
90.1
84.3
N.A.
70.8
76.3
N.A.
79
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
13.3
73.3
73.3
66.6
N.A.
26.6
40
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
86.6
93.3
80
N.A.
40
60
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
8
0
65
0
15
0
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
15
8
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
8
8
0
8
8
0
58
% D
% Glu:
0
0
0
8
0
0
8
0
0
0
8
15
72
29
15
% E
% Phe:
0
0
0
0
0
0
0
15
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
86
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
36
0
0
0
79
100
8
15
0
0
0
8
0
8
8
% L
% Met:
43
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
0
0
0
8
0
% N
% Pro:
0
0
0
8
8
0
0
0
0
86
79
8
0
0
8
% P
% Gln:
0
0
0
86
0
0
0
0
0
0
0
43
0
36
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
8
0
8
0
8
0
0
0
0
0
0
0
0
8
0
% S
% Thr:
0
0
86
0
0
0
8
0
65
0
8
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
8
0
0
0
0
0
43
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _