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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R3A
All Species:
22.73
Human Site:
S562
Identified Species:
41.67
UniProt:
Q06190
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06190
NP_002709.2
1150
130278
S562
E
P
K
S
K
V
S
S
P
I
E
K
V
S
P
Chimpanzee
Pan troglodytes
XP_001153482
1150
130149
S562
E
P
K
S
K
V
S
S
P
I
E
K
V
S
P
Rhesus Macaque
Macaca mulatta
XP_001115107
1150
130076
S562
E
P
K
S
K
V
S
S
P
I
E
K
V
S
P
Dog
Lupus familis
XP_542792
1152
130075
S561
E
P
K
S
K
V
S
S
P
T
E
K
V
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z176
491
55687
Rat
Rattus norvegicus
NP_001012202
1150
129888
S561
E
P
K
P
I
V
S
S
A
T
E
K
V
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518335
657
71327
N108
F
A
V
Q
S
T
C
N
L
K
D
I
A
G
E
Chicken
Gallus gallus
XP_422556
1117
125703
Y559
S
K
P
I
D
P
T
Y
P
L
S
K
I
V
E
Frog
Xenopus laevis
NP_001082623
1127
126700
S568
S
T
S
C
T
K
S
S
E
H
K
S
E
D
D
Zebra Danio
Brachydanio rerio
XP_694203
1163
130076
L585
G
N
S
V
V
K
D
L
P
V
V
G
F
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650842
888
97842
T339
S
A
D
S
K
P
A
T
K
E
K
P
T
A
V
Honey Bee
Apis mellifera
XP_396366
1240
138144
S609
T
N
N
N
S
F
N
S
T
E
Q
L
V
S
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784322
739
85352
D190
N
N
N
V
V
H
I
D
A
P
R
K
L
V
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.6
90.4
N.A.
27.8
85
N.A.
34
59.6
54
55.5
N.A.
32.6
30.7
N.A.
31.1
Protein Similarity:
100
99.7
98.8
94.6
N.A.
34.5
91
N.A.
43.1
73.3
68.7
70.8
N.A.
47.7
47.1
N.A.
45
P-Site Identity:
100
100
100
93.3
N.A.
0
73.3
N.A.
0
13.3
13.3
13.3
N.A.
13.3
20
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
0
73.3
N.A.
13.3
33.3
20
20
N.A.
40
40
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
0
8
0
16
0
0
0
8
8
0
% A
% Cys:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
8
8
0
0
8
0
0
8
8
% D
% Glu:
39
0
0
0
0
0
0
0
8
16
39
0
8
0
16
% E
% Phe:
8
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
8
0
8
8
% G
% His:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
8
8
0
8
0
0
24
0
8
8
0
0
% I
% Lys:
0
8
39
0
39
16
0
0
8
8
16
54
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
8
8
8
0
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
24
16
8
0
0
8
8
0
0
0
0
0
0
8
% N
% Pro:
0
39
8
8
0
16
0
0
47
8
0
8
0
0
39
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
24
0
16
39
16
0
47
54
0
0
8
8
0
54
0
% S
% Thr:
8
8
0
0
8
8
8
8
8
16
0
0
8
0
8
% T
% Val:
0
0
8
16
16
39
0
0
0
8
8
0
47
16
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _