KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R3A
All Species:
13.94
Human Site:
S376
Identified Species:
25.56
UniProt:
Q06190
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06190
NP_002709.2
1150
130278
S376
I
P
N
N
S
T
N
S
L
Y
N
L
E
V
N
Chimpanzee
Pan troglodytes
XP_001153482
1150
130149
S376
I
P
N
N
S
T
N
S
L
Y
N
L
E
V
N
Rhesus Macaque
Macaca mulatta
XP_001115107
1150
130076
S376
I
P
N
N
S
T
N
S
L
Y
N
L
E
V
N
Dog
Lupus familis
XP_542792
1152
130075
P376
I
P
N
N
S
T
N
P
L
Y
N
S
E
I
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z176
491
55687
Rat
Rattus norvegicus
NP_001012202
1150
129888
C376
P
N
N
T
N
S
L
C
S
L
E
V
N
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518335
657
71327
Chicken
Gallus gallus
XP_422556
1117
125703
I376
T
S
K
S
L
C
S
I
S
Q
E
N
S
V
R
Frog
Xenopus laevis
NP_001082623
1127
126700
K377
I
N
D
A
T
I
V
K
S
V
S
P
V
A
P
Zebra Danio
Brachydanio rerio
XP_694203
1163
130076
T382
V
P
G
L
S
A
R
T
P
P
S
T
N
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650842
888
97842
T156
T
L
K
K
S
D
I
T
T
A
N
G
K
V
K
Honey Bee
Apis mellifera
XP_396366
1240
138144
S416
I
T
S
P
T
A
S
S
N
L
D
D
S
S
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784322
739
85352
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.6
90.4
N.A.
27.8
85
N.A.
34
59.6
54
55.5
N.A.
32.6
30.7
N.A.
31.1
Protein Similarity:
100
99.7
98.8
94.6
N.A.
34.5
91
N.A.
43.1
73.3
68.7
70.8
N.A.
47.7
47.1
N.A.
45
P-Site Identity:
100
100
100
80
N.A.
0
6.6
N.A.
0
6.6
6.6
13.3
N.A.
20
13.3
N.A.
0
P-Site Similarity:
100
100
100
86.6
N.A.
0
26.6
N.A.
0
20
26.6
33.3
N.A.
33.3
40
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
16
0
0
0
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
0
0
0
0
8
8
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
16
0
31
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
8
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
47
0
0
0
0
8
8
8
0
0
0
0
0
8
0
% I
% Lys:
0
0
16
8
0
0
0
8
0
0
0
0
8
0
8
% K
% Leu:
0
8
0
8
8
0
8
0
31
16
0
24
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
16
39
31
8
0
31
0
8
0
39
8
16
0
31
% N
% Pro:
8
39
0
8
0
0
0
8
8
8
0
8
0
0
16
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% R
% Ser:
0
8
8
8
47
8
16
31
24
0
16
8
16
8
0
% S
% Thr:
16
8
0
8
16
31
0
16
8
0
0
8
0
0
8
% T
% Val:
8
0
0
0
0
0
8
0
0
8
0
8
8
39
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
31
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _